Downstream Effects of Mutations in SOD1 and TARDBP Converge on Gene Expression Impairment in Patient-Derived Motor Neurons

Amyotrophic Lateral Sclerosis (ALS) is a progressive and fatal neurodegenerative disease marked by death of motor neurons (MNs) present in the spinal cord, brain stem and motor cortex. Despite extensive research, the reason for neurodegeneration is still not understood. To generate novel hypotheses...

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Detalles Bibliográficos
Autores principales: Dash, Banaja P., Freischmidt, Axel, Weishaupt, Jochen H., Hermann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456253/
https://www.ncbi.nlm.nih.gov/pubmed/36077049
http://dx.doi.org/10.3390/ijms23179652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456253/
https://www.ncbi.nlm.nih.gov/pubmed/36077049
http://dx.doi.org/10.3390/ijms23179652

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