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Transoral Tongue Suspension for Obstructive Sleep Apnea—A Preliminary Study

Objectives: To evaluate the safety and efficacy of a novel technique for transoral tongue suspension (TOTS) in obstructive sleep apnea (OSA) patients. Material and Methods: The retrospective study enrolled 24 consecutive OSA patients (21 males; average age, 43 years; average apnea–hypopnea index (AH...

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Autores principales: Hsin, Li-Jen, Lee, Yi-Chan, Lin, Wan-Ni, Lu, Yi-An, Lee, Li-Ang, Tsai, Ming-Shao, Cheng, Wen-Nuan, Chiang, Yen-Ting, Li, Hsueh-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456292/
https://www.ncbi.nlm.nih.gov/pubmed/36078891
http://dx.doi.org/10.3390/jcm11174960
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author Hsin, Li-Jen
Lee, Yi-Chan
Lin, Wan-Ni
Lu, Yi-An
Lee, Li-Ang
Tsai, Ming-Shao
Cheng, Wen-Nuan
Chiang, Yen-Ting
Li, Hsueh-Yu
author_facet Hsin, Li-Jen
Lee, Yi-Chan
Lin, Wan-Ni
Lu, Yi-An
Lee, Li-Ang
Tsai, Ming-Shao
Cheng, Wen-Nuan
Chiang, Yen-Ting
Li, Hsueh-Yu
author_sort Hsin, Li-Jen
collection PubMed
description Objectives: To evaluate the safety and efficacy of a novel technique for transoral tongue suspension (TOTS) in obstructive sleep apnea (OSA) patients. Material and Methods: The retrospective study enrolled 24 consecutive OSA patients (21 males; average age, 43 years; average apnea–hypopnea index (AHI), 42.2 event/h; average body mass index (BMI), 25.7 kg/m(2)) with tongue obstruction confirmed by drug-induced sleep endoscopy. All patients received TOTS as the main procedure in conjunction with uvulopalatopharyngoplasty (UPPP). Key procedures of TOTS included a transoral sublabial approach, drilling two holes on the mandible, passing the polypropylene through the hole to the tongue base using a suture passer and returning the polypropylene through loop traction, and tying the polypropylene to the mandible. Lingual tonsil ablation (n = 8) was also implemented in hypertrophic lingual tonsils (grades III and IV). Results: The operation time for TOTS was around 30 min. No wound bleeding or airway compromise occurred throughout the postoperative period. Minor complications were temporary and included swelling of the tongue, numbness of the lower incisor, and sublabial wound dehiscence (n = 2). The quality of life improved significantly in the patients’ subjective daytime sleepiness according to the Epworth Sleepiness Scale (11.4 ± 3.2 vs. 5.7 ± 1.6, p < 0.001). The objective parameters of OSA also improved significantly in the apnea/hypopnea index (42.2 ± 21.8 vs. 19.5 ± 16.2, p < 0.001), minimal oxygen saturation (77.1 ± 12.2 vs. 81.7 ± 8.1, p = 0.026), and snoring index (207 ± 141 vs. 101 ± 91, p = 0.03). Conclusions: The demonstrated TOTS showed its advantage in low morbidity with a scarless exterior and easy performance with free availability in treating adult OSA patients with tongue obstruction. TOTS combined with UPPP significantly improved AHI and daytime sleepiness. TOTS can be implemented with lingual tonsillectomy to achieve both stabilization of the tongue and widening of hypopharyngeal airway.
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spelling pubmed-94562922022-09-09 Transoral Tongue Suspension for Obstructive Sleep Apnea—A Preliminary Study Hsin, Li-Jen Lee, Yi-Chan Lin, Wan-Ni Lu, Yi-An Lee, Li-Ang Tsai, Ming-Shao Cheng, Wen-Nuan Chiang, Yen-Ting Li, Hsueh-Yu J Clin Med Article Objectives: To evaluate the safety and efficacy of a novel technique for transoral tongue suspension (TOTS) in obstructive sleep apnea (OSA) patients. Material and Methods: The retrospective study enrolled 24 consecutive OSA patients (21 males; average age, 43 years; average apnea–hypopnea index (AHI), 42.2 event/h; average body mass index (BMI), 25.7 kg/m(2)) with tongue obstruction confirmed by drug-induced sleep endoscopy. All patients received TOTS as the main procedure in conjunction with uvulopalatopharyngoplasty (UPPP). Key procedures of TOTS included a transoral sublabial approach, drilling two holes on the mandible, passing the polypropylene through the hole to the tongue base using a suture passer and returning the polypropylene through loop traction, and tying the polypropylene to the mandible. Lingual tonsil ablation (n = 8) was also implemented in hypertrophic lingual tonsils (grades III and IV). Results: The operation time for TOTS was around 30 min. No wound bleeding or airway compromise occurred throughout the postoperative period. Minor complications were temporary and included swelling of the tongue, numbness of the lower incisor, and sublabial wound dehiscence (n = 2). The quality of life improved significantly in the patients’ subjective daytime sleepiness according to the Epworth Sleepiness Scale (11.4 ± 3.2 vs. 5.7 ± 1.6, p < 0.001). The objective parameters of OSA also improved significantly in the apnea/hypopnea index (42.2 ± 21.8 vs. 19.5 ± 16.2, p < 0.001), minimal oxygen saturation (77.1 ± 12.2 vs. 81.7 ± 8.1, p = 0.026), and snoring index (207 ± 141 vs. 101 ± 91, p = 0.03). Conclusions: The demonstrated TOTS showed its advantage in low morbidity with a scarless exterior and easy performance with free availability in treating adult OSA patients with tongue obstruction. TOTS combined with UPPP significantly improved AHI and daytime sleepiness. TOTS can be implemented with lingual tonsillectomy to achieve both stabilization of the tongue and widening of hypopharyngeal airway. MDPI 2022-08-24 /pmc/articles/PMC9456292/ /pubmed/36078891 http://dx.doi.org/10.3390/jcm11174960 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hsin, Li-Jen
Lee, Yi-Chan
Lin, Wan-Ni
Lu, Yi-An
Lee, Li-Ang
Tsai, Ming-Shao
Cheng, Wen-Nuan
Chiang, Yen-Ting
Li, Hsueh-Yu
Transoral Tongue Suspension for Obstructive Sleep Apnea—A Preliminary Study
title Transoral Tongue Suspension for Obstructive Sleep Apnea—A Preliminary Study
title_full Transoral Tongue Suspension for Obstructive Sleep Apnea—A Preliminary Study
title_fullStr Transoral Tongue Suspension for Obstructive Sleep Apnea—A Preliminary Study
title_full_unstemmed Transoral Tongue Suspension for Obstructive Sleep Apnea—A Preliminary Study
title_short Transoral Tongue Suspension for Obstructive Sleep Apnea—A Preliminary Study
title_sort transoral tongue suspension for obstructive sleep apnea—a preliminary study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456292/
https://www.ncbi.nlm.nih.gov/pubmed/36078891
http://dx.doi.org/10.3390/jcm11174960
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