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Comorbidity of Novel CRHR2 Gene Variants in Type 2 Diabetes and Depression
The corticotropin-releasing hormone receptor 2 (CRHR2) gene encodes CRHR2, contributing to the hypothalamic–pituitary–adrenal stress response and to hyperglycemia and insulin resistance. CRHR2−/− mice are hypersensitive to stress, and the CRHR2 locus has been linked to type 2 diabetes and depression...
Autores principales: | Amin, Mutaz, Ott, Jurg, Gordon, Derek, Wu, Rongling, Postolache, Teodor T., Vergare, Michael, Gragnoli, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456299/ https://www.ncbi.nlm.nih.gov/pubmed/36077219 http://dx.doi.org/10.3390/ijms23179819 |
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