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Efficacy Comparison of LPA(2) Antagonist H2L5186303 and Agonist GRI977143 on Ovalbumin-Induced Allergic Asthma in BALB/c Mice

Lysophosphatidic acid (LPA), an intercellular lipid mediator, is increased in the bronchoalveolar fluids of patients with asthma after allergen exposure. LPA administration exaggerates allergic responses, and the type 2 LPA receptor (LPA(2)) has been reported as a therapeutic target for asthma. Howe...

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Detalles Bibliográficos
Autores principales:	Lee, Ye-Ji, Im, Dong-Soon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456302/ https://www.ncbi.nlm.nih.gov/pubmed/36077141 http://dx.doi.org/10.3390/ijms23179745

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