Cargando…
Synthetic Secoisolariciresinol Diglucoside (LGM2605) Prevents Asbestos-Induced Inflammation and Genotoxic Cell Damage in Human Mesothelial Cells
Although alveolar macrophages play a critical role in malignant transformation of mesothelial cells following asbestos exposure, inflammatory and oxidative processes continue to occur in the mesothelial cells lining the pleura that may contribute to the carcinogenic process. Malignant transformation...
Autores principales: | Pietrofesa, Ralph A., Chatterjee, Shampa, Kadariya, Yuwaraj, Testa, Joseph R., Albelda, Steven M., Christofidou-Solomidou, Melpo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456329/ https://www.ncbi.nlm.nih.gov/pubmed/36077483 http://dx.doi.org/10.3390/ijms231710085 |
Ejemplares similares
-
Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605) Reduces Asbestos-Induced Cytotoxicity in an Nrf2-Dependent and -Independent Manner
por: Pietrofesa, Ralph A., et al.
Publicado: (2018) -
Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605)
por: Pietrofesa, Ralph A., et al.
Publicado: (2016) -
Synthetic Secoisolariciresinol Diglucoside (LGM2605) Protects Human Lung in an Ex Vivo Model of Proton Radiation Damage
por: Velalopoulou, Anastasia, et al.
Publicado: (2017) -
Copper Oxide Nanoparticle-Induced Acute Inflammatory Response and Injury in Murine Lung Is Ameliorated by Synthetic Secoisolariciresinol Diglucoside (LGM2605)
por: Pietrofesa, Ralph A., et al.
Publicado: (2021) -
The Synthetic Lignan Secoisolariciresinol Diglucoside Prevents Asbestos-Induced NLRP3 Inflammasome Activation in Murine Macrophages
por: Pietrofesa, Ralph A., et al.
Publicado: (2017)