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Chromosomal Instability Characterizes Pediatric Medulloblastoma but Is Not Tolerated in the Developing Cerebellum
Medulloblastoma is a pediatric brain malignancy that consists of four transcriptional subgroups. Structural and numerical aneuploidy are common in all subgroups, although they are particularly profound in Group 3 and Group 4 medulloblastoma and in a subtype of SHH medulloblastoma termed SHHα. This s...
Autores principales: | Bočkaj, Irena, Martini, Tosca E. I., Smit, Marlinde J., Armandari, Inna, Bakker, Bjorn, Wardenaar, René, Meeuwsen-de Boer, Tiny G. J., Bakker, Petra L., Spierings, Diana C. J., Hoving, Eelco W., Guryev, Victor, Foijer, Floris, Bruggeman, Sophia W. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456393/ https://www.ncbi.nlm.nih.gov/pubmed/36077248 http://dx.doi.org/10.3390/ijms23179852 |
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