The Oncolytic Adenovirus XVir-N-31, in Combination with the Blockade of the PD-1/PD-L1 Axis, Conveys Abscopal Effects in a Humanized Glioblastoma Mouse Model

Glioblastoma (GBM) is an obligatory lethal brain tumor with a median survival, even with the best standard of care therapy, of less than 20 months. In light of this fact, the evaluation of new GBM treatment approaches such as oncolytic virotherapy (OVT) is urgently needed. Based on our preliminary p...

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Detalles Bibliográficos
Autores principales: Klawitter, Moritz, El-Ayoubi, Ali, Buch, Jasmin, Rüttinger, Jakob, Ehrenfeld, Maximilian, Lichtenegger, Eva, Krüger, Marcel A., Mantwill, Klaus, Koll, Florestan J., Kowarik, Markus C., Holm, Per Sonne, Naumann, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456411/
https://www.ncbi.nlm.nih.gov/pubmed/36077380
http://dx.doi.org/10.3390/ijms23179965

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