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Aminopeptidase N Inhibitors as Pointers for Overcoming Antitumor Treatment Resistance
Aminopeptidase N (APN), also known as CD13 antigen or membrane alanyl aminopeptidase, belongs to the M1 family of the MA clan of zinc metallopeptidases. In cancer cells, the inhibition of aminopeptidases including APN causes the phenomenon termed the amino acid deprivation response (AADR), a stress...
Autores principales: | Farsa, Oldřich, Ballayová, Veronika, Žáčková, Radka, Kollar, Peter, Kauerová, Tereza, Zubáč, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456425/ https://www.ncbi.nlm.nih.gov/pubmed/36077208 http://dx.doi.org/10.3390/ijms23179813 |
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