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Dapagliflozin Mitigates Doxorubicin-Caused Myocardium Damage by Regulating AKT-Mediated Oxidative Stress, Cardiac Remodeling, and Inflammation
Doxorubicin (Dox) is a commonly used anthracycline chemotherapy with a side effect of cardiotoxicity, which may increase the risk of heart failure for cancer patients. Although various studies have demonstrated the cardioprotective property of dapagliflozin (DAPA), a sodium-glucose cotransporter 2 i...
Autores principales: | Hsieh, Pei-Ling, Chu, Pei-Ming, Cheng, Hui-Ching, Huang, Yu-Ting, Chou, Wan-Ching, Tsai, Kun-Ling, Chan, Shih-Hung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456438/ https://www.ncbi.nlm.nih.gov/pubmed/36077544 http://dx.doi.org/10.3390/ijms231710146 |
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