The NHE3 Inhibitor Tenapanor Prevents Intestinal Obstructions in CFTR-Deleted Mice

Mutations in the CFTR chloride channel result in intestinal obstructive episodes in cystic fibrosis (CF) patients and in CF animal models. In this study, we explored the possibility of reducing the frequency of obstructive episodes in cftr(−/−) mice through the oral application of a gut-selective NH...

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Detalles Bibliográficos
Autores principales: Tan, Xinjie, Kini, Archana, Römermann, Dorothee, Seidler, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456459/
https://www.ncbi.nlm.nih.gov/pubmed/36077390
http://dx.doi.org/10.3390/ijms23179993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456459/
https://www.ncbi.nlm.nih.gov/pubmed/36077390
http://dx.doi.org/10.3390/ijms23179993

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