Cargando…

In Vitro Characterization of Renal Drug Transporter Activity in Kidney Cancer

The activity of drug transporters is central to the secretory function of the kidneys and a defining feature of renal proximal tubule epithelial cells (RPTECs). The expression, regulation, and function of these membrane-bound proteins is well understood under normal renal physiological conditions. H...

Descripción completa

Detalles Bibliográficos
Autores principales:	Caetano-Pinto, Pedro, Justian, Nathanil, Dib, Maria, Fischer, Jana, Somova, Maryna, Burchardt, Martin, Wolff, Ingmar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456511/ https://www.ncbi.nlm.nih.gov/pubmed/36077583 http://dx.doi.org/10.3390/ijms231710177

Ejemplares similares

Recapitulating the Pharmacological Interactions of Cetuximab with Sunitinib and Cisplatin in Head and Neck Carcinoma Cells in vitro
por: Dib, Maria, et al.
Publicado: (2022)

Microfluidic-based prostate cancer model for investigating the secretion of prostate-specific antigen and microRNAs in vitro
por: Padmyastuti, Adventina, et al.
Publicado: (2023)

Kidney Cancer and Chronic Kidney Disease: Too Close for Comfort
por: Pinto, Pedro Caetano, et al.
Publicado: (2021)

Renal Organic Anion Transporters 1 and 3 In Vitro: Gone but Not Forgotten
por: Caetano-Pinto, Pedro, et al.
Publicado: (2023)

Cetuximab Prevents Methotrexate-Induced Cytotoxicity in Vitro through Epidermal Growth Factor Dependent Regulation of Renal Drug Transporters
por: Caetano-Pinto, Pedro, et al.
Publicado: (2017)

Assessment of the Role of Renal Organic Anion Transporters in Drug-Induced Nephrotoxicity
por: Hagos, Yohannes, et al.
Publicado: (2010)

Kidney Drug Transporters in Pharmacotherapy
por: Łapczuk-Romańska, Joanna, et al.
Publicado: (2023)

Renal drug transporters and their significance in drug–drug interactions
por: Yin, Jia, et al.
Publicado: (2016)

Sheep and Cattle Are Not Susceptible to Experimental Inoculation with Hazara Orthonairovirus, a Tick-Borne Arbovirus Closely Related to CCHFV
por: Hartlaub, Julia, et al.
Publicado: (2020)

Identification of the Regulatory Targets of miR-3687 and miR-4417 in Prostate Cancer Cells Using a Proteomics Approach
por: Venz, Simone, et al.
Publicado: (2022)

Assessment of Amino Acid/Drug Transporters for Renal Transport of [(18)F]Fluciclovine (anti-[(18)F]FACBC) in Vitro
por: Ono, Masahiro, et al.
Publicado: (2016)

Characterization of Rhodamine-123 as a Tracer Dye for Use In In vitro Drug Transport Assays
por: Forster, Samantha, et al.
Publicado: (2012)

Kidney Ischemia/Reperfusion Injury Induces Changes in the Drug Transporter Expression at the Blood–Brain Barrier in vivo and in vitro
por: Burek, Malgorzata, et al.
Publicado: (2020)

The role of drug transporters in the kidney: lessons from tenofovir
por: Moss, Darren M., et al.
Publicado: (2014)

Deregulated Renal Calcium and Phosphate Transport during Experimental Kidney Failure
por: Pulskens, Wilco P., et al.
Publicado: (2015)

Research Methods and New Advances in Drug–Drug Interactions Mediated by Renal Transporters
por: Lin, Kexin, et al.
Publicado: (2023)

Intraoperative prevention of postoperative hypoparathyroidism
por: Vabalayte, Kristina, et al.
Publicado: (2023)

Corrigendum: The role of drug transporters in the kidney: lessons from tenofovir
por: Moss, Darren M.
Publicado: (2015)

Protein Abundance of Clinically Relevant Drug Transporters in The Human Kidneys
por: Oswald, Stefan, et al.
Publicado: (2019)

Entecavir Interacts with Influx Transporters hOAT1, hCNT2, hCNT3, but Not with hOCT2: The Potential for Renal Transporter-Mediated Cytotoxicity and Drug–Drug Interactions
por: Mandíková, Jana, et al.
Publicado: (2016)

Renal denervation of the native kidneys for drug-resistant hypertension after kidney transplantation
por: Dobrowolski, Linn C., et al.
Publicado: (2015)

Are In Vitro Cytotoxicity Assessments of Environmental Samples Useful for Characterizing the Risk of Exposure to Multiple Contaminants at the Workplace? A Systematic Review
por: Viegas, Carla, et al.
Publicado: (2022)

The Impact of Genetic Polymorphisms in Organic Cation Transporters on Renal Drug Disposition
por: Zazuli, Zulfan, et al.
Publicado: (2020)

Impact of Viral Inflammation on the Expression of Renal Drug Transporters in Pregnant Rats
por: Karimian Pour, Navaz, et al.
Publicado: (2019)

Differential effects of nephrotoxic agents on renal transport and metabolism by use of in vitro techniques.
por: Hirsch, G H
Publicado: (1976)

Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport
por: Yeung, Catherine K., et al.
Publicado: (2013)

Expression of drug transporters in human kidney: impact of sex, age, and ethnicity
por: Joseph, Stancy, et al.
Publicado: (2015)

Extrahepatic Drug Transporters in Liver Failure: Focus on Kidney and Gastrointestinal Tract
por: Droździk, Marek, et al.
Publicado: (2020)

Evaluation of Pharmacogenetics of Drug-Metabolizing Enzymes and Drug Efflux Transporter in Renal Transplants Receiving Immunosuppressants
por: Sridharan, Kannan, et al.
Publicado: (2022)

Quantification of the cellular dose and characterization of nanoparticle transport during in vitro testing
por: Rischitor, Grigore, et al.
Publicado: (2016)

Characterization of Nanoparticle Intestinal Transport Using an In Vitro Co-Culture Model
por: Strugari, Alina F.G., et al.
Publicado: (2018)

Selenoprotein P Status Correlates to Cancer-Specific Mortality in Renal Cancer Patients
por: Meyer, Hellmuth A., et al.
Publicado: (2012)

Drug Transporters in the Kidney: Perspectives on Species Differences, Disease Status, and Molecular Docking
por: Zou, Wei, et al.
Publicado: (2021)

Novel targeted siRNA-loaded hybrid nanoparticles: preparation, characterization and in vitro evaluation
por: Dim, Nneka, et al.
Publicado: (2015)

Magma transport in sheet intrusions of the Alnö carbonatite complex, central Sweden
por: Andersson, Magnus, et al.
Publicado: (2016)

Cell geteromorphism in the conditions of persistence of sapronoses causative agents in various environments
por: Somova, Larisa M., et al.
Publicado: (2019)

Erratum to: Quantification of the cellular dose and characterization of nanoparticle transport during in vitro testing
por: Rischitor, Grigore, et al.
Publicado: (2016)

Novel In Vitro Models for Cell Differentiation and Drug Transport Studies of the Human Intestine
por: Przybylla, Randy, et al.
Publicado: (2023)

Role of Hepatocyte Transporters in Drug-Induced Liver Injury (DILI)—In Vitro Testing
por: Tátrai, Péter, et al.
Publicado: (2022)

The System Profile of Renal Drug Transporters in Tubulointerstitial Fibrosis Model and Consequent Effect on Pharmacokinetics
por: Shi, Birui, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_fj1rq59kq6vh8b0p53jmsmgu1u