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Update on Current Imaging of Systemic Lupus Erythematous in Adults and Juveniles
Systemic lupus erythematosus (SLE) is an autoimmune disease involving multiple organs and organ systems. Musculoskeletal (MSK) involvement is one of the most frequent and the earliest locations of disease. This disease affects joints and periarticular soft tissues, tendon sheaths and tendons, bones,...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456621/ https://www.ncbi.nlm.nih.gov/pubmed/36079142 http://dx.doi.org/10.3390/jcm11175212 |
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author | Sudoł-Szopińska, Iwona Żelnio, Ewa Olesińska, Marzena Gietka, Piotr Ornowska, Sylwia Power, Deborah Jane Taljanovic, Mihra S. |
author_facet | Sudoł-Szopińska, Iwona Żelnio, Ewa Olesińska, Marzena Gietka, Piotr Ornowska, Sylwia Power, Deborah Jane Taljanovic, Mihra S. |
author_sort | Sudoł-Szopińska, Iwona |
collection | PubMed |
description | Systemic lupus erythematosus (SLE) is an autoimmune disease involving multiple organs and organ systems. Musculoskeletal (MSK) involvement is one of the most frequent and the earliest locations of disease. This disease affects joints and periarticular soft tissues, tendon sheaths and tendons, bones, and muscles. Multimodality imaging, including radiography, ultrasound (US), and magnetic resonance imaging (MRI), plays a significant role in the initial evaluation and treatment follow up of MSK manifestations of the SLE. In this paper, we illustrate MSK imaging features in three clinical forms of SLE, including nondeforming nonerosive arthritis, deforming nonerosive arthropathy, and erosive arthropathy, as well as the other complications and features of SLE within the MSK system in adults and juveniles. Advances in imaging are included. Conventional radiography primarily shows late skeletal lesions, whereas the US and MRI are valuable in the diagnosis of the early inflammatory changes of the soft tissues and bone marrow, as well as late skeletal manifestations. In nondeforming nonerosive arthritis, US and MRI show effusions, synovial and/or tenosynovial hypertrophy, and vascularity, whereas radiographs are normal. Deforming arthritis clinically resembles that observed in rheumatoid arthritis, but it is reversible, and US and MRI show features of inflammation of periarticular soft tissues (capsule, ligaments, and tendons) without the pannus and destruction classically observed in RA. Erosions are rarely seen, and this form of disease is called rhupus syndrome. |
format | Online Article Text |
id | pubmed-9456621 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94566212022-09-09 Update on Current Imaging of Systemic Lupus Erythematous in Adults and Juveniles Sudoł-Szopińska, Iwona Żelnio, Ewa Olesińska, Marzena Gietka, Piotr Ornowska, Sylwia Power, Deborah Jane Taljanovic, Mihra S. J Clin Med Review Systemic lupus erythematosus (SLE) is an autoimmune disease involving multiple organs and organ systems. Musculoskeletal (MSK) involvement is one of the most frequent and the earliest locations of disease. This disease affects joints and periarticular soft tissues, tendon sheaths and tendons, bones, and muscles. Multimodality imaging, including radiography, ultrasound (US), and magnetic resonance imaging (MRI), plays a significant role in the initial evaluation and treatment follow up of MSK manifestations of the SLE. In this paper, we illustrate MSK imaging features in three clinical forms of SLE, including nondeforming nonerosive arthritis, deforming nonerosive arthropathy, and erosive arthropathy, as well as the other complications and features of SLE within the MSK system in adults and juveniles. Advances in imaging are included. Conventional radiography primarily shows late skeletal lesions, whereas the US and MRI are valuable in the diagnosis of the early inflammatory changes of the soft tissues and bone marrow, as well as late skeletal manifestations. In nondeforming nonerosive arthritis, US and MRI show effusions, synovial and/or tenosynovial hypertrophy, and vascularity, whereas radiographs are normal. Deforming arthritis clinically resembles that observed in rheumatoid arthritis, but it is reversible, and US and MRI show features of inflammation of periarticular soft tissues (capsule, ligaments, and tendons) without the pannus and destruction classically observed in RA. Erosions are rarely seen, and this form of disease is called rhupus syndrome. MDPI 2022-09-03 /pmc/articles/PMC9456621/ /pubmed/36079142 http://dx.doi.org/10.3390/jcm11175212 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sudoł-Szopińska, Iwona Żelnio, Ewa Olesińska, Marzena Gietka, Piotr Ornowska, Sylwia Power, Deborah Jane Taljanovic, Mihra S. Update on Current Imaging of Systemic Lupus Erythematous in Adults and Juveniles |
title | Update on Current Imaging of Systemic Lupus Erythematous in Adults and Juveniles |
title_full | Update on Current Imaging of Systemic Lupus Erythematous in Adults and Juveniles |
title_fullStr | Update on Current Imaging of Systemic Lupus Erythematous in Adults and Juveniles |
title_full_unstemmed | Update on Current Imaging of Systemic Lupus Erythematous in Adults and Juveniles |
title_short | Update on Current Imaging of Systemic Lupus Erythematous in Adults and Juveniles |
title_sort | update on current imaging of systemic lupus erythematous in adults and juveniles |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456621/ https://www.ncbi.nlm.nih.gov/pubmed/36079142 http://dx.doi.org/10.3390/jcm11175212 |
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