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KRAS‐G12D mutation drives immune suppression and the primary resistance of anti‐PD‐1/PD‐L1 immunotherapy in non‐small cell lung cancer

BACKGROUND: Although immune checkpoint inhibitors (ICIs) against programmed cell death protein 1 (PD‐1) and its ligand PD‐L1 have demonstrated potency towards treating patients with non‐small cell lung carcinoma (NSCLC), the potential association between Kirsten rat sarcoma viral oncogene homolog (K...

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Detalles Bibliográficos
Autores principales: Liu, Chengming, Zheng, Sufei, Wang, Zhanyu, Wang, Sihui, Wang, Xinfeng, Yang, Lu, Xu, Haiyan, Cao, Zheng, Feng, Xiaoli, Xue, Qi, Wang, Yan, Sun, Nan, He, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456691/
https://www.ncbi.nlm.nih.gov/pubmed/35811500
http://dx.doi.org/10.1002/cac2.12327

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