A Metal-Containing NP Approach to Treat Methicillin-Resistant Staphylococcus aureus (MRSA): Prospects and Challenges

Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of pneumonia in humans, and it is associated with high morbidity and mortality rates, especially in immunocompromised patients. Its high rate of multidrug resistance led to an exploration of novel antimicrobials. Metal nanopart...

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Autores principales: Yeo, Wendy Wai Yeng, Maran, Sathiya, Kong, Amanda Shen-Yee, Cheng, Wan-Hee, Lim, Swee-Hua Erin, Loh, Jiun-Yan, Lai, Kok-Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456709/
https://www.ncbi.nlm.nih.gov/pubmed/36079184
http://dx.doi.org/10.3390/ma15175802
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author Yeo, Wendy Wai Yeng
Maran, Sathiya
Kong, Amanda Shen-Yee
Cheng, Wan-Hee
Lim, Swee-Hua Erin
Loh, Jiun-Yan
Lai, Kok-Song
author_facet Yeo, Wendy Wai Yeng
Maran, Sathiya
Kong, Amanda Shen-Yee
Cheng, Wan-Hee
Lim, Swee-Hua Erin
Loh, Jiun-Yan
Lai, Kok-Song
author_sort Yeo, Wendy Wai Yeng
collection PubMed
description Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of pneumonia in humans, and it is associated with high morbidity and mortality rates, especially in immunocompromised patients. Its high rate of multidrug resistance led to an exploration of novel antimicrobials. Metal nanoparticles have shown potent antibacterial activity, thus instigating their application in MRSA. This review summarizes current insights of Metal-Containing NPs in treating MRSA. This review also provides an in-depth appraisal of opportunities and challenges in utilizing metal-NPs to treat MRSA.
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spelling pubmed-94567092022-09-09 A Metal-Containing NP Approach to Treat Methicillin-Resistant Staphylococcus aureus (MRSA): Prospects and Challenges Yeo, Wendy Wai Yeng Maran, Sathiya Kong, Amanda Shen-Yee Cheng, Wan-Hee Lim, Swee-Hua Erin Loh, Jiun-Yan Lai, Kok-Song Materials (Basel) Review Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of pneumonia in humans, and it is associated with high morbidity and mortality rates, especially in immunocompromised patients. Its high rate of multidrug resistance led to an exploration of novel antimicrobials. Metal nanoparticles have shown potent antibacterial activity, thus instigating their application in MRSA. This review summarizes current insights of Metal-Containing NPs in treating MRSA. This review also provides an in-depth appraisal of opportunities and challenges in utilizing metal-NPs to treat MRSA. MDPI 2022-08-23 /pmc/articles/PMC9456709/ /pubmed/36079184 http://dx.doi.org/10.3390/ma15175802 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Yeo, Wendy Wai Yeng
Maran, Sathiya
Kong, Amanda Shen-Yee
Cheng, Wan-Hee
Lim, Swee-Hua Erin
Loh, Jiun-Yan
Lai, Kok-Song
A Metal-Containing NP Approach to Treat Methicillin-Resistant Staphylococcus aureus (MRSA): Prospects and Challenges
title A Metal-Containing NP Approach to Treat Methicillin-Resistant Staphylococcus aureus (MRSA): Prospects and Challenges
title_full A Metal-Containing NP Approach to Treat Methicillin-Resistant Staphylococcus aureus (MRSA): Prospects and Challenges
title_fullStr A Metal-Containing NP Approach to Treat Methicillin-Resistant Staphylococcus aureus (MRSA): Prospects and Challenges
title_full_unstemmed A Metal-Containing NP Approach to Treat Methicillin-Resistant Staphylococcus aureus (MRSA): Prospects and Challenges
title_short A Metal-Containing NP Approach to Treat Methicillin-Resistant Staphylococcus aureus (MRSA): Prospects and Challenges
title_sort metal-containing np approach to treat methicillin-resistant staphylococcus aureus (mrsa): prospects and challenges
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456709/
https://www.ncbi.nlm.nih.gov/pubmed/36079184
http://dx.doi.org/10.3390/ma15175802
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