Sjögren Syndrome: New Insights in the Pathogenesis and Role of Nuclear Medicine

In the last years, new insights into the molecular basis of rheumatic conditions have been described, which have generated particular interest in understanding the pathophysiology of these diseases, in which lies the explanation of the diversity of clinical presentation and the difficulty in diagnos...

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Autores principales: Kelly, Anzola Luz, Nelson, Rivera Jose, Sara, Ramírez, Alberto, Signore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456759/
https://www.ncbi.nlm.nih.gov/pubmed/36079157
http://dx.doi.org/10.3390/jcm11175227
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author Kelly, Anzola Luz
Nelson, Rivera Jose
Sara, Ramírez
Alberto, Signore
author_facet Kelly, Anzola Luz
Nelson, Rivera Jose
Sara, Ramírez
Alberto, Signore
author_sort Kelly, Anzola Luz
collection PubMed
description In the last years, new insights into the molecular basis of rheumatic conditions have been described, which have generated particular interest in understanding the pathophysiology of these diseases, in which lies the explanation of the diversity of clinical presentation and the difficulty in diagnostic and therapeutic approaches. In this review, we focus on the new pathophysiological findings for Sjögren syndrome and on the derived new SPECT and PET radiopharmaceuticals to detect inflammation of immunological origin, focusing on their role in diagnosis, prognosis, and the evaluation of therapeutic efficacy.
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spelling pubmed-94567592022-09-09 Sjögren Syndrome: New Insights in the Pathogenesis and Role of Nuclear Medicine Kelly, Anzola Luz Nelson, Rivera Jose Sara, Ramírez Alberto, Signore J Clin Med Review In the last years, new insights into the molecular basis of rheumatic conditions have been described, which have generated particular interest in understanding the pathophysiology of these diseases, in which lies the explanation of the diversity of clinical presentation and the difficulty in diagnostic and therapeutic approaches. In this review, we focus on the new pathophysiological findings for Sjögren syndrome and on the derived new SPECT and PET radiopharmaceuticals to detect inflammation of immunological origin, focusing on their role in diagnosis, prognosis, and the evaluation of therapeutic efficacy. MDPI 2022-09-04 /pmc/articles/PMC9456759/ /pubmed/36079157 http://dx.doi.org/10.3390/jcm11175227 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kelly, Anzola Luz
Nelson, Rivera Jose
Sara, Ramírez
Alberto, Signore
Sjögren Syndrome: New Insights in the Pathogenesis and Role of Nuclear Medicine
title Sjögren Syndrome: New Insights in the Pathogenesis and Role of Nuclear Medicine
title_full Sjögren Syndrome: New Insights in the Pathogenesis and Role of Nuclear Medicine
title_fullStr Sjögren Syndrome: New Insights in the Pathogenesis and Role of Nuclear Medicine
title_full_unstemmed Sjögren Syndrome: New Insights in the Pathogenesis and Role of Nuclear Medicine
title_short Sjögren Syndrome: New Insights in the Pathogenesis and Role of Nuclear Medicine
title_sort sjögren syndrome: new insights in the pathogenesis and role of nuclear medicine
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9456759/
https://www.ncbi.nlm.nih.gov/pubmed/36079157
http://dx.doi.org/10.3390/jcm11175227
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