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Obesity Surgery Improves Hypogonadism and Sexual Function in Men without Effects in Sperm Quality

(1) Background: Obesity is associated with hypogonadism, sexual dysfunction, and impaired fertility in men. However, its effects on semen parameters or sexual function remain debatable. (2) Methods: This paper involves a longitudinal study in men submitted for obesity surgery at a university tertiar...

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Autores principales: Miñambres, Inka, Sardà, Helena, Urgell, Eulalia, Genua, Idoia, Ramos, Analía, Fernández-Ananin, Sonia, Balagué, Carmen, Sánchez-Quesada, Jose Luis, Bassas, Lluís, Pérez, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457146/
https://www.ncbi.nlm.nih.gov/pubmed/36079056
http://dx.doi.org/10.3390/jcm11175126
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author Miñambres, Inka
Sardà, Helena
Urgell, Eulalia
Genua, Idoia
Ramos, Analía
Fernández-Ananin, Sonia
Balagué, Carmen
Sánchez-Quesada, Jose Luis
Bassas, Lluís
Pérez, Antonio
author_facet Miñambres, Inka
Sardà, Helena
Urgell, Eulalia
Genua, Idoia
Ramos, Analía
Fernández-Ananin, Sonia
Balagué, Carmen
Sánchez-Quesada, Jose Luis
Bassas, Lluís
Pérez, Antonio
author_sort Miñambres, Inka
collection PubMed
description (1) Background: Obesity is associated with hypogonadism, sexual dysfunction, and impaired fertility in men. However, its effects on semen parameters or sexual function remain debatable. (2) Methods: This paper involves a longitudinal study in men submitted for obesity surgery at a university tertiary hospital. Patients were studied at baseline and at 6, 12, and 18 months after obesity surgery. At each visit, anthropometry measures were collected and hormonal and semen parameters were studied. Sexual function was evaluated with the International Index of Erectile Function (IIEF). (3) Results: A total of 12 patients were included. The average body mass index of patients decreased from 42.37 ± 4.44 to 29.6 ± 3.77 kg/m(2) at 18 months after surgery (p < 0.05). Hormonal parameters improved after obesity surgery. The proportion of sperm cells with normal morphology tended to decrease from baseline and became most significant at 18 months (5.83 ± 4.50 vs. 2.82 ± 2.08). No significant changes were found in the remaining semen parameters. Erectile function improved significantly at six months after surgery. (4) Conclusions: The authors believe that, in general, the effects of obesity surgery on fertility may be limited or even deleterious (at least in the short and midterm follow-up).
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spelling pubmed-94571462022-09-09 Obesity Surgery Improves Hypogonadism and Sexual Function in Men without Effects in Sperm Quality Miñambres, Inka Sardà, Helena Urgell, Eulalia Genua, Idoia Ramos, Analía Fernández-Ananin, Sonia Balagué, Carmen Sánchez-Quesada, Jose Luis Bassas, Lluís Pérez, Antonio J Clin Med Article (1) Background: Obesity is associated with hypogonadism, sexual dysfunction, and impaired fertility in men. However, its effects on semen parameters or sexual function remain debatable. (2) Methods: This paper involves a longitudinal study in men submitted for obesity surgery at a university tertiary hospital. Patients were studied at baseline and at 6, 12, and 18 months after obesity surgery. At each visit, anthropometry measures were collected and hormonal and semen parameters were studied. Sexual function was evaluated with the International Index of Erectile Function (IIEF). (3) Results: A total of 12 patients were included. The average body mass index of patients decreased from 42.37 ± 4.44 to 29.6 ± 3.77 kg/m(2) at 18 months after surgery (p < 0.05). Hormonal parameters improved after obesity surgery. The proportion of sperm cells with normal morphology tended to decrease from baseline and became most significant at 18 months (5.83 ± 4.50 vs. 2.82 ± 2.08). No significant changes were found in the remaining semen parameters. Erectile function improved significantly at six months after surgery. (4) Conclusions: The authors believe that, in general, the effects of obesity surgery on fertility may be limited or even deleterious (at least in the short and midterm follow-up). MDPI 2022-08-31 /pmc/articles/PMC9457146/ /pubmed/36079056 http://dx.doi.org/10.3390/jcm11175126 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Miñambres, Inka
Sardà, Helena
Urgell, Eulalia
Genua, Idoia
Ramos, Analía
Fernández-Ananin, Sonia
Balagué, Carmen
Sánchez-Quesada, Jose Luis
Bassas, Lluís
Pérez, Antonio
Obesity Surgery Improves Hypogonadism and Sexual Function in Men without Effects in Sperm Quality
title Obesity Surgery Improves Hypogonadism and Sexual Function in Men without Effects in Sperm Quality
title_full Obesity Surgery Improves Hypogonadism and Sexual Function in Men without Effects in Sperm Quality
title_fullStr Obesity Surgery Improves Hypogonadism and Sexual Function in Men without Effects in Sperm Quality
title_full_unstemmed Obesity Surgery Improves Hypogonadism and Sexual Function in Men without Effects in Sperm Quality
title_short Obesity Surgery Improves Hypogonadism and Sexual Function in Men without Effects in Sperm Quality
title_sort obesity surgery improves hypogonadism and sexual function in men without effects in sperm quality
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457146/
https://www.ncbi.nlm.nih.gov/pubmed/36079056
http://dx.doi.org/10.3390/jcm11175126
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