Identification of cap-dependent endonuclease inhibitors with broad-spectrum activity against bunyaviruses

Viral hemorrhagic fevers caused by members of the order Bunyavirales comprise endemic and emerging human infections that are significant public health concerns. Despite the disease severity, there are few therapeutic options available, and therefore effective antiviral drugs are urgently needed to r...

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Detalles Bibliográficos
Autores principales: Toba, Shinsuke, Sato, Akihiko, Kawai, Makoto, Taoda, Yoshiyuki, Unoh, Yuto, Kusakabe, Shinji, Nobori, Haruaki, Uehara, Shota, Uemura, Kentaro, Taniguchi, Keiichi, Kobayashi, Masanori, Noshi, Takeshi, Yoshida, Ryu, Naito, Akira, Shishido, Takao, Maruyama, Junki, Paessler, Slobodan, Carr, Michael J., Hall, William W., Yoshimatsu, Kumiko, Arikawa, Jiro, Matsuno, Keita, Sakoda, Yoshihiro, Sasaki, Michihito, Orba, Yasuko, Sawa, Hirofumi, Kida, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457168/
https://www.ncbi.nlm.nih.gov/pubmed/36037386
http://dx.doi.org/10.1073/pnas.2206104119

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