Cargando…

National Information Campaign Revealed Disease Characteristic and Burden in Adult Patients Suffering from Atopic Dermatitis

Atopic dermatitis (AD) is a common inflammatory skin disease often associated with a significant impairment in the quality of life of affected patients. The Italian Society of Dermatology and Venereology (SIDeMaST) planned a national information campaign, providing direct access to 27 dermatologic c...

Descripción completa

Detalles Bibliográficos
Autores principales: Gori, Niccolò, Chiricozzi, Andrea, Marsili, Franco, Ferrucci, Silvia Mariel, Amerio, Paolo, Battarra, Vincenzo, Campitiello, Salvatore, Castelli, Antonio, Congedo, Maurizio, Corazza, Monica, Cristaudo, Antonio, Fabbrocini, Gabriella, Girolomoni, Giampiero, Malara, Giovanna, Micali, Giuseppe, Palazzo, Giovanni, Parodi, Aurora, Patrizi, Annalisa, Pellacani, Giovanni, Pigatto, Paolo, Provenzano, Eugenio, Quaglino, Pietro, Romanelli, Marco, Rossi, Mariateresa, Savoia, Paola, Peris, Ketty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457191/
https://www.ncbi.nlm.nih.gov/pubmed/36079131
http://dx.doi.org/10.3390/jcm11175204
_version_ 1784785995827249152
author Gori, Niccolò
Chiricozzi, Andrea
Marsili, Franco
Ferrucci, Silvia Mariel
Amerio, Paolo
Battarra, Vincenzo
Campitiello, Salvatore
Castelli, Antonio
Congedo, Maurizio
Corazza, Monica
Cristaudo, Antonio
Fabbrocini, Gabriella
Girolomoni, Giampiero
Malara, Giovanna
Micali, Giuseppe
Palazzo, Giovanni
Parodi, Aurora
Patrizi, Annalisa
Pellacani, Giovanni
Pigatto, Paolo
Provenzano, Eugenio
Quaglino, Pietro
Romanelli, Marco
Rossi, Mariateresa
Savoia, Paola
Peris, Ketty
author_facet Gori, Niccolò
Chiricozzi, Andrea
Marsili, Franco
Ferrucci, Silvia Mariel
Amerio, Paolo
Battarra, Vincenzo
Campitiello, Salvatore
Castelli, Antonio
Congedo, Maurizio
Corazza, Monica
Cristaudo, Antonio
Fabbrocini, Gabriella
Girolomoni, Giampiero
Malara, Giovanna
Micali, Giuseppe
Palazzo, Giovanni
Parodi, Aurora
Patrizi, Annalisa
Pellacani, Giovanni
Pigatto, Paolo
Provenzano, Eugenio
Quaglino, Pietro
Romanelli, Marco
Rossi, Mariateresa
Savoia, Paola
Peris, Ketty
author_sort Gori, Niccolò
collection PubMed
description Atopic dermatitis (AD) is a common inflammatory skin disease often associated with a significant impairment in the quality of life of affected patients. The Italian Society of Dermatology and Venereology (SIDeMaST) planned a national information campaign, providing direct access to 27 dermatologic centers dedicated to the management of AD. The aim of this study aimed was to outline critical aspects related to AD in the general population. Overall, 643 adult subjects were included in this study, and in 44.2% (284/643) of cases, a diagnosis of AD was confirmed, whereas about 55% of subjects were affected by other pruritic cutaneous diseases. Higher intensity of pruritus and sleep disturbance, as well as an increased interference in sport, work, and social confidence was reported in the AD group compared to the non-AD group. In the AD subgroup, the mean duration of disease was of 15.3 years, with a mean eczema area and severity index (EASI) score of 11.2, and investigator global assessment (IGA) score of 1.9 and an itch numeric rating scale (NRS) of 6.9. Almost 32% of patients were untreated, either with topical or systemic agents, whereas 44.3% used routine topical compounds (topical corticosteroids and calcineurin inhibitors), and only 7.0% of patients were systemically treated. Only 2.8% of patients reported complete satisfaction with the treatment received for AD to date. This study reveals a profound unmet need in AD, showing a poorly managed and undertreated patient population despite a high reported burden of disease. This suggests the usefulness of information campaigns with the goal of improving patient awareness regarding AD and facilitating early diagnosis and access to dedicated healthcare institutions.
format Online
Article
Text
id pubmed-9457191
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-94571912022-09-09 National Information Campaign Revealed Disease Characteristic and Burden in Adult Patients Suffering from Atopic Dermatitis Gori, Niccolò Chiricozzi, Andrea Marsili, Franco Ferrucci, Silvia Mariel Amerio, Paolo Battarra, Vincenzo Campitiello, Salvatore Castelli, Antonio Congedo, Maurizio Corazza, Monica Cristaudo, Antonio Fabbrocini, Gabriella Girolomoni, Giampiero Malara, Giovanna Micali, Giuseppe Palazzo, Giovanni Parodi, Aurora Patrizi, Annalisa Pellacani, Giovanni Pigatto, Paolo Provenzano, Eugenio Quaglino, Pietro Romanelli, Marco Rossi, Mariateresa Savoia, Paola Peris, Ketty J Clin Med Article Atopic dermatitis (AD) is a common inflammatory skin disease often associated with a significant impairment in the quality of life of affected patients. The Italian Society of Dermatology and Venereology (SIDeMaST) planned a national information campaign, providing direct access to 27 dermatologic centers dedicated to the management of AD. The aim of this study aimed was to outline critical aspects related to AD in the general population. Overall, 643 adult subjects were included in this study, and in 44.2% (284/643) of cases, a diagnosis of AD was confirmed, whereas about 55% of subjects were affected by other pruritic cutaneous diseases. Higher intensity of pruritus and sleep disturbance, as well as an increased interference in sport, work, and social confidence was reported in the AD group compared to the non-AD group. In the AD subgroup, the mean duration of disease was of 15.3 years, with a mean eczema area and severity index (EASI) score of 11.2, and investigator global assessment (IGA) score of 1.9 and an itch numeric rating scale (NRS) of 6.9. Almost 32% of patients were untreated, either with topical or systemic agents, whereas 44.3% used routine topical compounds (topical corticosteroids and calcineurin inhibitors), and only 7.0% of patients were systemically treated. Only 2.8% of patients reported complete satisfaction with the treatment received for AD to date. This study reveals a profound unmet need in AD, showing a poorly managed and undertreated patient population despite a high reported burden of disease. This suggests the usefulness of information campaigns with the goal of improving patient awareness regarding AD and facilitating early diagnosis and access to dedicated healthcare institutions. MDPI 2022-09-02 /pmc/articles/PMC9457191/ /pubmed/36079131 http://dx.doi.org/10.3390/jcm11175204 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gori, Niccolò
Chiricozzi, Andrea
Marsili, Franco
Ferrucci, Silvia Mariel
Amerio, Paolo
Battarra, Vincenzo
Campitiello, Salvatore
Castelli, Antonio
Congedo, Maurizio
Corazza, Monica
Cristaudo, Antonio
Fabbrocini, Gabriella
Girolomoni, Giampiero
Malara, Giovanna
Micali, Giuseppe
Palazzo, Giovanni
Parodi, Aurora
Patrizi, Annalisa
Pellacani, Giovanni
Pigatto, Paolo
Provenzano, Eugenio
Quaglino, Pietro
Romanelli, Marco
Rossi, Mariateresa
Savoia, Paola
Peris, Ketty
National Information Campaign Revealed Disease Characteristic and Burden in Adult Patients Suffering from Atopic Dermatitis
title National Information Campaign Revealed Disease Characteristic and Burden in Adult Patients Suffering from Atopic Dermatitis
title_full National Information Campaign Revealed Disease Characteristic and Burden in Adult Patients Suffering from Atopic Dermatitis
title_fullStr National Information Campaign Revealed Disease Characteristic and Burden in Adult Patients Suffering from Atopic Dermatitis
title_full_unstemmed National Information Campaign Revealed Disease Characteristic and Burden in Adult Patients Suffering from Atopic Dermatitis
title_short National Information Campaign Revealed Disease Characteristic and Burden in Adult Patients Suffering from Atopic Dermatitis
title_sort national information campaign revealed disease characteristic and burden in adult patients suffering from atopic dermatitis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457191/
https://www.ncbi.nlm.nih.gov/pubmed/36079131
http://dx.doi.org/10.3390/jcm11175204
work_keys_str_mv AT goriniccolo nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT chiricozziandrea nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT marsilifranco nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT ferruccisilviamariel nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT ameriopaolo nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT battarravincenzo nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT campitiellosalvatore nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT castelliantonio nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT congedomaurizio nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT corazzamonica nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT cristaudoantonio nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT fabbrocinigabriella nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT girolomonigiampiero nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT malaragiovanna nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT micaligiuseppe nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT palazzogiovanni nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT parodiaurora nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT patriziannalisa nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT pellacanigiovanni nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT pigattopaolo nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT provenzanoeugenio nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT quaglinopietro nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT romanellimarco nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT rossimariateresa nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT savoiapaola nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis
AT perisketty nationalinformationcampaignrevealeddiseasecharacteristicandburdeninadultpatientssufferingfromatopicdermatitis