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Effects of on-Table Extubation after Pediatric Cardiac Surgery

Background: Enhanced recovery after surgery (ERAS) protocols are utilizing a multidisciplinary approach, reassessing physiology to improve clinical outcomes, reducing length of hospital stay (LOS) stay, resulting in cost reduction. Since its introduction in colorectal surgery. the concept has been u...

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Autores principales: Baehner, Torsten, Pruemm, Philipp, Vergnat, Mathieu, Asfour, Boulos, Straßberger-Nerschbach, Nadine, Kirfel, Andrea, Hamann, Michael, Mayr, Andreas, Schindler, Ehrenfried, Velten, Markus, Wittmann, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457288/
https://www.ncbi.nlm.nih.gov/pubmed/36079121
http://dx.doi.org/10.3390/jcm11175186
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author Baehner, Torsten
Pruemm, Philipp
Vergnat, Mathieu
Asfour, Boulos
Straßberger-Nerschbach, Nadine
Kirfel, Andrea
Hamann, Michael
Mayr, Andreas
Schindler, Ehrenfried
Velten, Markus
Wittmann, Maria
author_facet Baehner, Torsten
Pruemm, Philipp
Vergnat, Mathieu
Asfour, Boulos
Straßberger-Nerschbach, Nadine
Kirfel, Andrea
Hamann, Michael
Mayr, Andreas
Schindler, Ehrenfried
Velten, Markus
Wittmann, Maria
author_sort Baehner, Torsten
collection PubMed
description Background: Enhanced recovery after surgery (ERAS) protocols are utilizing a multidisciplinary approach, reassessing physiology to improve clinical outcomes, reducing length of hospital stay (LOS) stay, resulting in cost reduction. Since its introduction in colorectal surgery. the concept has been utilized in various fields and benefits have been recognized also in adult cardiac surgery. However, ERAS concepts in pediatric cardiac surgery are not yet widely established. Therefore, the aim of the present study was to assess the effects of on-table extubation (OTE) after pediatric cardiac surgery compared to the standard approach of delayed extubation (DET) during intensive care treatment. Study Design and Methods: We performed a retrospective analysis of all pediatric cardiac surgery cases performed in children below the age of two years using cardiopulmonary bypass at our institution in 2021. Exclusion criteria were emergency and off pump surgeries as well as children already ventilated preoperatively. Results: OTE children were older (267.3 days vs. 126.7 days, p < 0.001), had a higher body weight (7.0 ± 1.6 kg vs. 4.9 ± 1.9 kg, p < 0.001), showed significantly reduced duration of ICU treatment (75.9 ± 56.8 h vs. 217.2 ± 211.4 h, p < 0.001) and LOS (11.1 ± 10.2 days vs. 20.1 ± 23.4 days; p = 0.001) compared to DET group. Furthermore, OTE children had significantly fewer catecholamine dependencies at 12-, 24-, 48-, and 72-h post-surgery, while DET children showed a significantly increased intrafluid shift relative to body weight (109.1 ± 82.0 mL/kg body weight vs. 63.0 ± 63.0 mL/kg body weight, p < 0.001). After propensity score matching considering age, weight, bypass duration, Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery Mortality (STATS)-Score, and the outcome variables, including duration of ICU treatment, catecholamine dependencies, and hospital LOS, findings significantly favored the OTE group. Conclusion: Our results suggest that on-table extubation after pediatric cardiac surgery is feasible and in our cohort was associated with a favorable postoperative course.
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spelling pubmed-94572882022-09-09 Effects of on-Table Extubation after Pediatric Cardiac Surgery Baehner, Torsten Pruemm, Philipp Vergnat, Mathieu Asfour, Boulos Straßberger-Nerschbach, Nadine Kirfel, Andrea Hamann, Michael Mayr, Andreas Schindler, Ehrenfried Velten, Markus Wittmann, Maria J Clin Med Article Background: Enhanced recovery after surgery (ERAS) protocols are utilizing a multidisciplinary approach, reassessing physiology to improve clinical outcomes, reducing length of hospital stay (LOS) stay, resulting in cost reduction. Since its introduction in colorectal surgery. the concept has been utilized in various fields and benefits have been recognized also in adult cardiac surgery. However, ERAS concepts in pediatric cardiac surgery are not yet widely established. Therefore, the aim of the present study was to assess the effects of on-table extubation (OTE) after pediatric cardiac surgery compared to the standard approach of delayed extubation (DET) during intensive care treatment. Study Design and Methods: We performed a retrospective analysis of all pediatric cardiac surgery cases performed in children below the age of two years using cardiopulmonary bypass at our institution in 2021. Exclusion criteria were emergency and off pump surgeries as well as children already ventilated preoperatively. Results: OTE children were older (267.3 days vs. 126.7 days, p < 0.001), had a higher body weight (7.0 ± 1.6 kg vs. 4.9 ± 1.9 kg, p < 0.001), showed significantly reduced duration of ICU treatment (75.9 ± 56.8 h vs. 217.2 ± 211.4 h, p < 0.001) and LOS (11.1 ± 10.2 days vs. 20.1 ± 23.4 days; p = 0.001) compared to DET group. Furthermore, OTE children had significantly fewer catecholamine dependencies at 12-, 24-, 48-, and 72-h post-surgery, while DET children showed a significantly increased intrafluid shift relative to body weight (109.1 ± 82.0 mL/kg body weight vs. 63.0 ± 63.0 mL/kg body weight, p < 0.001). After propensity score matching considering age, weight, bypass duration, Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery Mortality (STATS)-Score, and the outcome variables, including duration of ICU treatment, catecholamine dependencies, and hospital LOS, findings significantly favored the OTE group. Conclusion: Our results suggest that on-table extubation after pediatric cardiac surgery is feasible and in our cohort was associated with a favorable postoperative course. MDPI 2022-09-01 /pmc/articles/PMC9457288/ /pubmed/36079121 http://dx.doi.org/10.3390/jcm11175186 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Baehner, Torsten
Pruemm, Philipp
Vergnat, Mathieu
Asfour, Boulos
Straßberger-Nerschbach, Nadine
Kirfel, Andrea
Hamann, Michael
Mayr, Andreas
Schindler, Ehrenfried
Velten, Markus
Wittmann, Maria
Effects of on-Table Extubation after Pediatric Cardiac Surgery
title Effects of on-Table Extubation after Pediatric Cardiac Surgery
title_full Effects of on-Table Extubation after Pediatric Cardiac Surgery
title_fullStr Effects of on-Table Extubation after Pediatric Cardiac Surgery
title_full_unstemmed Effects of on-Table Extubation after Pediatric Cardiac Surgery
title_short Effects of on-Table Extubation after Pediatric Cardiac Surgery
title_sort effects of on-table extubation after pediatric cardiac surgery
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457288/
https://www.ncbi.nlm.nih.gov/pubmed/36079121
http://dx.doi.org/10.3390/jcm11175186
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