Cargando…

The Safety and Efficacy of Vela Laser En-Bloc Endoscopic Resection versus Conventional Transurethral Resection of Bladder Tumor—A Single Center Experience

(1) Background: The current gold standard treatment of bladder cancer is conventional transurethral resection of the bladder tumor (CTURBT) using monopolar or bipolar resectoscopes. Laser en-bloc resection of the bladder tumor (LERBT) could achieve a higher quality of the specimen, reduce perioperat...

Descripción completa

Detalles Bibliográficos
Autores principales: Chang, Che-Wei, Tang, Tsz-Yi, Geng, Jiun-Hung, Jhan, Jhen-Hao, Wang, Hsun-Shuan, Shen, Jung-Tsung, Lee, Yung-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457292/
https://www.ncbi.nlm.nih.gov/pubmed/36079164
http://dx.doi.org/10.3390/jcm11175233
_version_ 1784786019378266112
author Chang, Che-Wei
Tang, Tsz-Yi
Geng, Jiun-Hung
Jhan, Jhen-Hao
Wang, Hsun-Shuan
Shen, Jung-Tsung
Lee, Yung-Chin
author_facet Chang, Che-Wei
Tang, Tsz-Yi
Geng, Jiun-Hung
Jhan, Jhen-Hao
Wang, Hsun-Shuan
Shen, Jung-Tsung
Lee, Yung-Chin
author_sort Chang, Che-Wei
collection PubMed
description (1) Background: The current gold standard treatment of bladder cancer is conventional transurethral resection of the bladder tumor (CTURBT) using monopolar or bipolar resectoscopes. Laser en-bloc resection of the bladder tumor (LERBT) could achieve a higher quality of the specimen, reduce perioperative complications, and decrease the recurrence rate. Here, we compare the efficacy and safety of en-bloc Vela laser resection versus the conventional monopolar/bipolar resection; (2) Methods: A total of 100 clinically cT1-2 patients with bladder cancer were retrospectively reviewed in this study. Among these patients, 50 patients received LERBT, and 50 patients received CTURBT. The baseline characteristics, operation variables, and clinical outcomes were collected. The primary performance was the presence of muscle layer in the specimen. Perioperative complications and recurrence-free survival (RFS) were also compared. Independent t-test, Chi-square test, Kaplan–Meier curves, and the Cox-regression model were used in the analysis; (3) Results: The median age of the patients in the laser and resectoscope groups was 69.2 and 68.0 years old, respectively. The statistical difference in the presence of the detrusor muscle was 92.0% in the laser group and 70.0% in the CTURBT group (p = 0.005). A lower incidence of bladder perforation (p = 0.041) and major surgical complications (p = 0.046) in the LEBRT group was observed. We found no differences in operation duration, catheterization time, and hospitalization time after adjustment. Additionally, there was no statistical difference in RFS after a median follow-up time of 25 months; (4) Conclusions: Endoscopic laser en-bloc resection of bladder tumor with Vela laser is an effective method with higher muscle inclusion rate and fewer complications.
format Online
Article
Text
id pubmed-9457292
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-94572922022-09-09 The Safety and Efficacy of Vela Laser En-Bloc Endoscopic Resection versus Conventional Transurethral Resection of Bladder Tumor—A Single Center Experience Chang, Che-Wei Tang, Tsz-Yi Geng, Jiun-Hung Jhan, Jhen-Hao Wang, Hsun-Shuan Shen, Jung-Tsung Lee, Yung-Chin J Clin Med Article (1) Background: The current gold standard treatment of bladder cancer is conventional transurethral resection of the bladder tumor (CTURBT) using monopolar or bipolar resectoscopes. Laser en-bloc resection of the bladder tumor (LERBT) could achieve a higher quality of the specimen, reduce perioperative complications, and decrease the recurrence rate. Here, we compare the efficacy and safety of en-bloc Vela laser resection versus the conventional monopolar/bipolar resection; (2) Methods: A total of 100 clinically cT1-2 patients with bladder cancer were retrospectively reviewed in this study. Among these patients, 50 patients received LERBT, and 50 patients received CTURBT. The baseline characteristics, operation variables, and clinical outcomes were collected. The primary performance was the presence of muscle layer in the specimen. Perioperative complications and recurrence-free survival (RFS) were also compared. Independent t-test, Chi-square test, Kaplan–Meier curves, and the Cox-regression model were used in the analysis; (3) Results: The median age of the patients in the laser and resectoscope groups was 69.2 and 68.0 years old, respectively. The statistical difference in the presence of the detrusor muscle was 92.0% in the laser group and 70.0% in the CTURBT group (p = 0.005). A lower incidence of bladder perforation (p = 0.041) and major surgical complications (p = 0.046) in the LEBRT group was observed. We found no differences in operation duration, catheterization time, and hospitalization time after adjustment. Additionally, there was no statistical difference in RFS after a median follow-up time of 25 months; (4) Conclusions: Endoscopic laser en-bloc resection of bladder tumor with Vela laser is an effective method with higher muscle inclusion rate and fewer complications. MDPI 2022-09-05 /pmc/articles/PMC9457292/ /pubmed/36079164 http://dx.doi.org/10.3390/jcm11175233 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chang, Che-Wei
Tang, Tsz-Yi
Geng, Jiun-Hung
Jhan, Jhen-Hao
Wang, Hsun-Shuan
Shen, Jung-Tsung
Lee, Yung-Chin
The Safety and Efficacy of Vela Laser En-Bloc Endoscopic Resection versus Conventional Transurethral Resection of Bladder Tumor—A Single Center Experience
title The Safety and Efficacy of Vela Laser En-Bloc Endoscopic Resection versus Conventional Transurethral Resection of Bladder Tumor—A Single Center Experience
title_full The Safety and Efficacy of Vela Laser En-Bloc Endoscopic Resection versus Conventional Transurethral Resection of Bladder Tumor—A Single Center Experience
title_fullStr The Safety and Efficacy of Vela Laser En-Bloc Endoscopic Resection versus Conventional Transurethral Resection of Bladder Tumor—A Single Center Experience
title_full_unstemmed The Safety and Efficacy of Vela Laser En-Bloc Endoscopic Resection versus Conventional Transurethral Resection of Bladder Tumor—A Single Center Experience
title_short The Safety and Efficacy of Vela Laser En-Bloc Endoscopic Resection versus Conventional Transurethral Resection of Bladder Tumor—A Single Center Experience
title_sort safety and efficacy of vela laser en-bloc endoscopic resection versus conventional transurethral resection of bladder tumor—a single center experience
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457292/
https://www.ncbi.nlm.nih.gov/pubmed/36079164
http://dx.doi.org/10.3390/jcm11175233
work_keys_str_mv AT changchewei thesafetyandefficacyofvelalaserenblocendoscopicresectionversusconventionaltransurethralresectionofbladdertumorasinglecenterexperience
AT tangtszyi thesafetyandefficacyofvelalaserenblocendoscopicresectionversusconventionaltransurethralresectionofbladdertumorasinglecenterexperience
AT gengjiunhung thesafetyandefficacyofvelalaserenblocendoscopicresectionversusconventionaltransurethralresectionofbladdertumorasinglecenterexperience
AT jhanjhenhao thesafetyandefficacyofvelalaserenblocendoscopicresectionversusconventionaltransurethralresectionofbladdertumorasinglecenterexperience
AT wanghsunshuan thesafetyandefficacyofvelalaserenblocendoscopicresectionversusconventionaltransurethralresectionofbladdertumorasinglecenterexperience
AT shenjungtsung thesafetyandefficacyofvelalaserenblocendoscopicresectionversusconventionaltransurethralresectionofbladdertumorasinglecenterexperience
AT leeyungchin thesafetyandefficacyofvelalaserenblocendoscopicresectionversusconventionaltransurethralresectionofbladdertumorasinglecenterexperience
AT changchewei safetyandefficacyofvelalaserenblocendoscopicresectionversusconventionaltransurethralresectionofbladdertumorasinglecenterexperience
AT tangtszyi safetyandefficacyofvelalaserenblocendoscopicresectionversusconventionaltransurethralresectionofbladdertumorasinglecenterexperience
AT gengjiunhung safetyandefficacyofvelalaserenblocendoscopicresectionversusconventionaltransurethralresectionofbladdertumorasinglecenterexperience
AT jhanjhenhao safetyandefficacyofvelalaserenblocendoscopicresectionversusconventionaltransurethralresectionofbladdertumorasinglecenterexperience
AT wanghsunshuan safetyandefficacyofvelalaserenblocendoscopicresectionversusconventionaltransurethralresectionofbladdertumorasinglecenterexperience
AT shenjungtsung safetyandefficacyofvelalaserenblocendoscopicresectionversusconventionaltransurethralresectionofbladdertumorasinglecenterexperience
AT leeyungchin safetyandefficacyofvelalaserenblocendoscopicresectionversusconventionaltransurethralresectionofbladdertumorasinglecenterexperience