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A Real-Life Action toward the End of HIV Pandemic: Surveillance of Mother-to-Child HIV Transmission in a Center from Southeast Romania

Preventing mother-to-child HIV transmission is a strategy to eliminate new infections to move toward a world free of HIV/AIDS. The aim of this study is to assess the effectiveness of the perinatal infection prevention program in a single center from southeast Romania. Newborns of HIV-positive mother...

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Autores principales: Arbune, Manuela, Calin, Alina Mihaela, Iancu, Alina Viorica, Dumitru, Caterina Nela, Arbune, Anca Adriana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457399/
https://www.ncbi.nlm.nih.gov/pubmed/36078949
http://dx.doi.org/10.3390/jcm11175020
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author Arbune, Manuela
Calin, Alina Mihaela
Iancu, Alina Viorica
Dumitru, Caterina Nela
Arbune, Anca Adriana
author_facet Arbune, Manuela
Calin, Alina Mihaela
Iancu, Alina Viorica
Dumitru, Caterina Nela
Arbune, Anca Adriana
author_sort Arbune, Manuela
collection PubMed
description Preventing mother-to-child HIV transmission is a strategy to eliminate new infections to move toward a world free of HIV/AIDS. The aim of this study is to assess the effectiveness of the perinatal infection prevention program in a single center from southeast Romania. Newborns of HIV-positive mothers from 2005 to 2020 were followed-up until the age of two in a retrospective study. The transmission rate from HIV-positive mothers to living children was zero, but neonatal mortality, preterm birth and birth defects were still high. The peculiarity of our study is the high proportion of mothers with a nosocomial pattern of HIV transmission. Intensifying the efforts for accurate implementing the interventions for the prevention of mother-to-child HIV transmission, a long time follow-up for HIV-exposed uninfected children and new research on related HIV pregnancies are necessary to reach the objective of a new generation free of HIV.
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spelling pubmed-94573992022-09-09 A Real-Life Action toward the End of HIV Pandemic: Surveillance of Mother-to-Child HIV Transmission in a Center from Southeast Romania Arbune, Manuela Calin, Alina Mihaela Iancu, Alina Viorica Dumitru, Caterina Nela Arbune, Anca Adriana J Clin Med Article Preventing mother-to-child HIV transmission is a strategy to eliminate new infections to move toward a world free of HIV/AIDS. The aim of this study is to assess the effectiveness of the perinatal infection prevention program in a single center from southeast Romania. Newborns of HIV-positive mothers from 2005 to 2020 were followed-up until the age of two in a retrospective study. The transmission rate from HIV-positive mothers to living children was zero, but neonatal mortality, preterm birth and birth defects were still high. The peculiarity of our study is the high proportion of mothers with a nosocomial pattern of HIV transmission. Intensifying the efforts for accurate implementing the interventions for the prevention of mother-to-child HIV transmission, a long time follow-up for HIV-exposed uninfected children and new research on related HIV pregnancies are necessary to reach the objective of a new generation free of HIV. MDPI 2022-08-26 /pmc/articles/PMC9457399/ /pubmed/36078949 http://dx.doi.org/10.3390/jcm11175020 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Arbune, Manuela
Calin, Alina Mihaela
Iancu, Alina Viorica
Dumitru, Caterina Nela
Arbune, Anca Adriana
A Real-Life Action toward the End of HIV Pandemic: Surveillance of Mother-to-Child HIV Transmission in a Center from Southeast Romania
title A Real-Life Action toward the End of HIV Pandemic: Surveillance of Mother-to-Child HIV Transmission in a Center from Southeast Romania
title_full A Real-Life Action toward the End of HIV Pandemic: Surveillance of Mother-to-Child HIV Transmission in a Center from Southeast Romania
title_fullStr A Real-Life Action toward the End of HIV Pandemic: Surveillance of Mother-to-Child HIV Transmission in a Center from Southeast Romania
title_full_unstemmed A Real-Life Action toward the End of HIV Pandemic: Surveillance of Mother-to-Child HIV Transmission in a Center from Southeast Romania
title_short A Real-Life Action toward the End of HIV Pandemic: Surveillance of Mother-to-Child HIV Transmission in a Center from Southeast Romania
title_sort real-life action toward the end of hiv pandemic: surveillance of mother-to-child hiv transmission in a center from southeast romania
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457399/
https://www.ncbi.nlm.nih.gov/pubmed/36078949
http://dx.doi.org/10.3390/jcm11175020
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