Optimization of Bifunctional Antisense Oligonucleotides for Regulation of Mutually Exclusive Alternative Splicing of PKM Gene

Oligonucleotide tools, as modulators of alternative splicing, have been extensively studied, giving a rise to new therapeutic approaches. In this article, we report detailed research on the optimization of bifunctional antisense oligonucleotides (BASOs), which are targeted towards interactions with...

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Detalles Bibliográficos
Autores principales: Bartyś, Natalia, Pasternak, Anna, Lisowiec-Wąchnicka, Jolanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457596/
https://www.ncbi.nlm.nih.gov/pubmed/36080449
http://dx.doi.org/10.3390/molecules27175682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457596/
https://www.ncbi.nlm.nih.gov/pubmed/36080449
http://dx.doi.org/10.3390/molecules27175682

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