A Supramolecular Approach to Antimicrobial Surfaces

In this paper, we report on the preparation of Imidazole-functionalized glass surfaces, demonstrating the ability of a dinuclear Cu(II) complex of a macrocyclic ligand to give a “cascade” interaction with the deprotonated forms of grafted imidazole moieties. In this way, we realized a prototypal exa...

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Detalles Bibliográficos
Autores principales: Gazzola, Valentina, Grisoli, Pietro, Amendola, Valeria, Dacarro, Giacomo, Mangano, Carlo, Pallavicini, Piersandro, Poggi, Antonio, Rossi, Silvia, Vigani, Barbara, Taglietti, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457607/
https://www.ncbi.nlm.nih.gov/pubmed/36080495
http://dx.doi.org/10.3390/molecules27175731
Descripción
Sumario:In this paper, we report on the preparation of Imidazole-functionalized glass surfaces, demonstrating the ability of a dinuclear Cu(II) complex of a macrocyclic ligand to give a “cascade” interaction with the deprotonated forms of grafted imidazole moieties. In this way, we realized a prototypal example of an antimicrobial surface based on a supramolecular approach, obtaining a neat microbicidal effect using low amounts of the described copper complex.

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