A Supramolecular Approach to Antimicrobial Surfaces

In this paper, we report on the preparation of Imidazole-functionalized glass surfaces, demonstrating the ability of a dinuclear Cu(II) complex of a macrocyclic ligand to give a “cascade” interaction with the deprotonated forms of grafted imidazole moieties. In this way, we realized a prototypal exa...

Descripción completa

Detalles Bibliográficos
Autores principales: Gazzola, Valentina, Grisoli, Pietro, Amendola, Valeria, Dacarro, Giacomo, Mangano, Carlo, Pallavicini, Piersandro, Poggi, Antonio, Rossi, Silvia, Vigani, Barbara, Taglietti, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457607/
https://www.ncbi.nlm.nih.gov/pubmed/36080495
http://dx.doi.org/10.3390/molecules27175731
_version_ 1784786097162682368
author Gazzola, Valentina
Grisoli, Pietro
Amendola, Valeria
Dacarro, Giacomo
Mangano, Carlo
Pallavicini, Piersandro
Poggi, Antonio
Rossi, Silvia
Vigani, Barbara
Taglietti, Angelo
author_facet Gazzola, Valentina
Grisoli, Pietro
Amendola, Valeria
Dacarro, Giacomo
Mangano, Carlo
Pallavicini, Piersandro
Poggi, Antonio
Rossi, Silvia
Vigani, Barbara
Taglietti, Angelo
author_sort Gazzola, Valentina
collection PubMed
description In this paper, we report on the preparation of Imidazole-functionalized glass surfaces, demonstrating the ability of a dinuclear Cu(II) complex of a macrocyclic ligand to give a “cascade” interaction with the deprotonated forms of grafted imidazole moieties. In this way, we realized a prototypal example of an antimicrobial surface based on a supramolecular approach, obtaining a neat microbicidal effect using low amounts of the described copper complex.
format Online
Article
Text
id pubmed-9457607
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-94576072022-09-09 A Supramolecular Approach to Antimicrobial Surfaces Gazzola, Valentina Grisoli, Pietro Amendola, Valeria Dacarro, Giacomo Mangano, Carlo Pallavicini, Piersandro Poggi, Antonio Rossi, Silvia Vigani, Barbara Taglietti, Angelo Molecules Article In this paper, we report on the preparation of Imidazole-functionalized glass surfaces, demonstrating the ability of a dinuclear Cu(II) complex of a macrocyclic ligand to give a “cascade” interaction with the deprotonated forms of grafted imidazole moieties. In this way, we realized a prototypal example of an antimicrobial surface based on a supramolecular approach, obtaining a neat microbicidal effect using low amounts of the described copper complex. MDPI 2022-09-05 /pmc/articles/PMC9457607/ /pubmed/36080495 http://dx.doi.org/10.3390/molecules27175731 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gazzola, Valentina
Grisoli, Pietro
Amendola, Valeria
Dacarro, Giacomo
Mangano, Carlo
Pallavicini, Piersandro
Poggi, Antonio
Rossi, Silvia
Vigani, Barbara
Taglietti, Angelo
A Supramolecular Approach to Antimicrobial Surfaces
title A Supramolecular Approach to Antimicrobial Surfaces
title_full A Supramolecular Approach to Antimicrobial Surfaces
title_fullStr A Supramolecular Approach to Antimicrobial Surfaces
title_full_unstemmed A Supramolecular Approach to Antimicrobial Surfaces
title_short A Supramolecular Approach to Antimicrobial Surfaces
title_sort supramolecular approach to antimicrobial surfaces
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457607/
https://www.ncbi.nlm.nih.gov/pubmed/36080495
http://dx.doi.org/10.3390/molecules27175731
work_keys_str_mv AT gazzolavalentina asupramolecularapproachtoantimicrobialsurfaces
AT grisolipietro asupramolecularapproachtoantimicrobialsurfaces
AT amendolavaleria asupramolecularapproachtoantimicrobialsurfaces
AT dacarrogiacomo asupramolecularapproachtoantimicrobialsurfaces
AT manganocarlo asupramolecularapproachtoantimicrobialsurfaces
AT pallavicinipiersandro asupramolecularapproachtoantimicrobialsurfaces
AT poggiantonio asupramolecularapproachtoantimicrobialsurfaces
AT rossisilvia asupramolecularapproachtoantimicrobialsurfaces
AT viganibarbara asupramolecularapproachtoantimicrobialsurfaces
AT tagliettiangelo asupramolecularapproachtoantimicrobialsurfaces
AT gazzolavalentina supramolecularapproachtoantimicrobialsurfaces
AT grisolipietro supramolecularapproachtoantimicrobialsurfaces
AT amendolavaleria supramolecularapproachtoantimicrobialsurfaces
AT dacarrogiacomo supramolecularapproachtoantimicrobialsurfaces
AT manganocarlo supramolecularapproachtoantimicrobialsurfaces
AT pallavicinipiersandro supramolecularapproachtoantimicrobialsurfaces
AT poggiantonio supramolecularapproachtoantimicrobialsurfaces
AT rossisilvia supramolecularapproachtoantimicrobialsurfaces
AT viganibarbara supramolecularapproachtoantimicrobialsurfaces
AT tagliettiangelo supramolecularapproachtoantimicrobialsurfaces

Ejemplares similares