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Discovery of Some Heterocyclic Molecules as Bone Morphogenetic Protein 2 (BMP-2)-Inducible Kinase Inhibitors: Virtual Screening, ADME Properties, and Molecular Docking Simulations

Bone morphogenetic proteins (BMPs) are growth factors that have a vital role in the production of bone, cartilage, ligaments, and tendons. Tumors’ upregulation of bone morphogenetic proteins (BMPs) and their receptors are key features of cancer progression. Regulation of the BMP kinase system is a n...

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Detalles Bibliográficos
Autores principales: Belal, Amany, Elkady, Hazem, Al-Karmalawy, Ahmed A., Amin, Ali H., Ghoneim, Mohammed M., El-Sherbiny, Mohamed, Al-Serwi, Rasha Hamed, Abdou, Mohamed Attia, Ibrahim, Mona H., Mehany, Ahmed B. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457949/
https://www.ncbi.nlm.nih.gov/pubmed/36080338
http://dx.doi.org/10.3390/molecules27175571