Cargando…

New Myrtenal–Adamantane Conjugates Alleviate Alzheimer’s-Type Dementia in Rat Model

Alzheimer’s disease (AD) is a neurodegenerative disease associated with memory impairment and other central nervous system (CNS) symptoms. Two myrtenal–adamantane conjugates (MACs) showed excellent CNS potential against Alzheimer’s models. Adamantane is a common pharmacophore for drug design, and my...

Descripción completa

Detalles Bibliográficos
Autores principales: Dragomanova, Stela, Lazarova, Maria, Munkuev, Aldar, Suslov, Evgeniy, Volcho, Konstantin, Salakhutdinov, Nariman, Bibi, Amina, Reynisson, Jóhannes, Tzvetanova, Elina, Alexandrova, Albena, Georgieva, Almira, Uzunova, Diamara, Stefanova, Miroslava, Kalfin, Reni, Tancheva, Lyubka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457974/
https://www.ncbi.nlm.nih.gov/pubmed/36080227
http://dx.doi.org/10.3390/molecules27175456