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2-(Nitroaryl)-5-Substituted-1,3,4-Thiadiazole Derivatives with Antiprotozoal Activities: In Vitro and In Vivo Study

Nitro-containing compounds are a well-known class of anti-infective agents, especially in the field of anti-parasitic drug discovery. HAT or sleeping sickness is a neglected tropical disease caused by a protozoan parasite, Trypanosoma brucei. Following the approval of fexinidazole as the first oral...

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Detalles Bibliográficos
Autores principales: Mousavi, Alireza, Foroumadi, Parham, Emamgholipour, Zahra, Mäser, Pascal, Kaiser, Marcel, Foroumadi, Alireza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9457997/
https://www.ncbi.nlm.nih.gov/pubmed/36080325
http://dx.doi.org/10.3390/molecules27175559