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Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration
Maintenance hemodialysis induces water-soluble vitamins and trace elements losses, which is why recommendations regarding potential supplementation were provided, but mainly based on conventional hemodialysis. This study′s aim was to measure the water–soluble vitamins and trace element losses during...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458110/ https://www.ncbi.nlm.nih.gov/pubmed/36079711 http://dx.doi.org/10.3390/nu14173454 |
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author | Bévier, Alban Novel-Catin, Etienne Blond, Emilie Pelletier, Solenne Parant, Francois Koppe, Laetitia Fouque, Denis |
author_facet | Bévier, Alban Novel-Catin, Etienne Blond, Emilie Pelletier, Solenne Parant, Francois Koppe, Laetitia Fouque, Denis |
author_sort | Bévier, Alban |
collection | PubMed |
description | Maintenance hemodialysis induces water-soluble vitamins and trace elements losses, which is why recommendations regarding potential supplementation were provided, but mainly based on conventional hemodialysis. This study′s aim was to measure the water–soluble vitamins and trace element losses during one on-line post-dilution hemodiafiltration (HDF) session. Thirty-nine patients under maintenance HDF were enrolled. We used the Theraflux(®) sampler (Theradial Corp., Orvault, France) to analyze the full session dialysate mass transfer. Blood and dialysate samples were collected before and after one HDF session to measure B1, B2, B6, B9, B12, C vitamins, zinc, and selenium concentrations. Values significantly decreased for B1 (20.2%), B2 (13%), B6 (25.4%), B9 (32.6%), C (66.6%) and selenium (6.7%). No significant differences were found for vitamin B12 and zinc. The dialysate losses per session were 1.12 ± 0.88 mg for vitamin B1, 0.28 ± 0.30 mg for B2, 0.33 ± 0.09 mg for B6, 0.3 ± 0.18 mg for B9, 147.5 ± 145.50 mg for C and 25.75 ± 6.91 mg for zinc. Vitamin B12 and selenium were under detection values. In conclusion, during a standard 4hr-HDF session, we found important losses for vitamin B1, B6, B9, C and zinc, suggesting the need for regular monitoring of plasma levels and systematic supplementation of these compounds. |
format | Online Article Text |
id | pubmed-9458110 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-94581102022-09-09 Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration Bévier, Alban Novel-Catin, Etienne Blond, Emilie Pelletier, Solenne Parant, Francois Koppe, Laetitia Fouque, Denis Nutrients Article Maintenance hemodialysis induces water-soluble vitamins and trace elements losses, which is why recommendations regarding potential supplementation were provided, but mainly based on conventional hemodialysis. This study′s aim was to measure the water–soluble vitamins and trace element losses during one on-line post-dilution hemodiafiltration (HDF) session. Thirty-nine patients under maintenance HDF were enrolled. We used the Theraflux(®) sampler (Theradial Corp., Orvault, France) to analyze the full session dialysate mass transfer. Blood and dialysate samples were collected before and after one HDF session to measure B1, B2, B6, B9, B12, C vitamins, zinc, and selenium concentrations. Values significantly decreased for B1 (20.2%), B2 (13%), B6 (25.4%), B9 (32.6%), C (66.6%) and selenium (6.7%). No significant differences were found for vitamin B12 and zinc. The dialysate losses per session were 1.12 ± 0.88 mg for vitamin B1, 0.28 ± 0.30 mg for B2, 0.33 ± 0.09 mg for B6, 0.3 ± 0.18 mg for B9, 147.5 ± 145.50 mg for C and 25.75 ± 6.91 mg for zinc. Vitamin B12 and selenium were under detection values. In conclusion, during a standard 4hr-HDF session, we found important losses for vitamin B1, B6, B9, C and zinc, suggesting the need for regular monitoring of plasma levels and systematic supplementation of these compounds. MDPI 2022-08-23 /pmc/articles/PMC9458110/ /pubmed/36079711 http://dx.doi.org/10.3390/nu14173454 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bévier, Alban Novel-Catin, Etienne Blond, Emilie Pelletier, Solenne Parant, Francois Koppe, Laetitia Fouque, Denis Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration |
title | Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration |
title_full | Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration |
title_fullStr | Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration |
title_full_unstemmed | Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration |
title_short | Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration |
title_sort | water-soluble vitamins and trace elements losses during on-line hemodiafiltration |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458110/ https://www.ncbi.nlm.nih.gov/pubmed/36079711 http://dx.doi.org/10.3390/nu14173454 |
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