Cargando…

Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration

Maintenance hemodialysis induces water-soluble vitamins and trace elements losses, which is why recommendations regarding potential supplementation were provided, but mainly based on conventional hemodialysis. This study′s aim was to measure the water–soluble vitamins and trace element losses during...

Descripción completa

Detalles Bibliográficos
Autores principales: Bévier, Alban, Novel-Catin, Etienne, Blond, Emilie, Pelletier, Solenne, Parant, Francois, Koppe, Laetitia, Fouque, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458110/
https://www.ncbi.nlm.nih.gov/pubmed/36079711
http://dx.doi.org/10.3390/nu14173454
_version_ 1784786221328760832
author Bévier, Alban
Novel-Catin, Etienne
Blond, Emilie
Pelletier, Solenne
Parant, Francois
Koppe, Laetitia
Fouque, Denis
author_facet Bévier, Alban
Novel-Catin, Etienne
Blond, Emilie
Pelletier, Solenne
Parant, Francois
Koppe, Laetitia
Fouque, Denis
author_sort Bévier, Alban
collection PubMed
description Maintenance hemodialysis induces water-soluble vitamins and trace elements losses, which is why recommendations regarding potential supplementation were provided, but mainly based on conventional hemodialysis. This study′s aim was to measure the water–soluble vitamins and trace element losses during one on-line post-dilution hemodiafiltration (HDF) session. Thirty-nine patients under maintenance HDF were enrolled. We used the Theraflux(®) sampler (Theradial Corp., Orvault, France) to analyze the full session dialysate mass transfer. Blood and dialysate samples were collected before and after one HDF session to measure B1, B2, B6, B9, B12, C vitamins, zinc, and selenium concentrations. Values significantly decreased for B1 (20.2%), B2 (13%), B6 (25.4%), B9 (32.6%), C (66.6%) and selenium (6.7%). No significant differences were found for vitamin B12 and zinc. The dialysate losses per session were 1.12 ± 0.88 mg for vitamin B1, 0.28 ± 0.30 mg for B2, 0.33 ± 0.09 mg for B6, 0.3 ± 0.18 mg for B9, 147.5 ± 145.50 mg for C and 25.75 ± 6.91 mg for zinc. Vitamin B12 and selenium were under detection values. In conclusion, during a standard 4hr-HDF session, we found important losses for vitamin B1, B6, B9, C and zinc, suggesting the need for regular monitoring of plasma levels and systematic supplementation of these compounds.
format Online
Article
Text
id pubmed-9458110
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-94581102022-09-09 Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration Bévier, Alban Novel-Catin, Etienne Blond, Emilie Pelletier, Solenne Parant, Francois Koppe, Laetitia Fouque, Denis Nutrients Article Maintenance hemodialysis induces water-soluble vitamins and trace elements losses, which is why recommendations regarding potential supplementation were provided, but mainly based on conventional hemodialysis. This study′s aim was to measure the water–soluble vitamins and trace element losses during one on-line post-dilution hemodiafiltration (HDF) session. Thirty-nine patients under maintenance HDF were enrolled. We used the Theraflux(®) sampler (Theradial Corp., Orvault, France) to analyze the full session dialysate mass transfer. Blood and dialysate samples were collected before and after one HDF session to measure B1, B2, B6, B9, B12, C vitamins, zinc, and selenium concentrations. Values significantly decreased for B1 (20.2%), B2 (13%), B6 (25.4%), B9 (32.6%), C (66.6%) and selenium (6.7%). No significant differences were found for vitamin B12 and zinc. The dialysate losses per session were 1.12 ± 0.88 mg for vitamin B1, 0.28 ± 0.30 mg for B2, 0.33 ± 0.09 mg for B6, 0.3 ± 0.18 mg for B9, 147.5 ± 145.50 mg for C and 25.75 ± 6.91 mg for zinc. Vitamin B12 and selenium were under detection values. In conclusion, during a standard 4hr-HDF session, we found important losses for vitamin B1, B6, B9, C and zinc, suggesting the need for regular monitoring of plasma levels and systematic supplementation of these compounds. MDPI 2022-08-23 /pmc/articles/PMC9458110/ /pubmed/36079711 http://dx.doi.org/10.3390/nu14173454 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bévier, Alban
Novel-Catin, Etienne
Blond, Emilie
Pelletier, Solenne
Parant, Francois
Koppe, Laetitia
Fouque, Denis
Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration
title Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration
title_full Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration
title_fullStr Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration
title_full_unstemmed Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration
title_short Water-Soluble Vitamins and Trace Elements Losses during On-Line Hemodiafiltration
title_sort water-soluble vitamins and trace elements losses during on-line hemodiafiltration
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458110/
https://www.ncbi.nlm.nih.gov/pubmed/36079711
http://dx.doi.org/10.3390/nu14173454
work_keys_str_mv AT bevieralban watersolublevitaminsandtraceelementslossesduringonlinehemodiafiltration
AT novelcatinetienne watersolublevitaminsandtraceelementslossesduringonlinehemodiafiltration
AT blondemilie watersolublevitaminsandtraceelementslossesduringonlinehemodiafiltration
AT pelletiersolenne watersolublevitaminsandtraceelementslossesduringonlinehemodiafiltration
AT parantfrancois watersolublevitaminsandtraceelementslossesduringonlinehemodiafiltration
AT koppelaetitia watersolublevitaminsandtraceelementslossesduringonlinehemodiafiltration
AT fouquedenis watersolublevitaminsandtraceelementslossesduringonlinehemodiafiltration