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BCI-215, a Dual-Specificity Phosphatase Inhibitor, Reduces UVB-Induced Pigmentation in Human Skin by Activating Mitogen-Activated Protein Kinase Pathways

Background: The dysregulation of melanin production causes skin-disfiguring ultraviolet (UV)-associated hyperpigmented spots. Previously, we found that the activation of c-Jun N-terminal kinase (JNK), a mitogen-activated protein kinase (MAPK), inhibited melanogenesis. Methods: We selected BCI-215 as...

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Detalles Bibliográficos
Autores principales:	Lee, Jeong Hyeon, Choi, Myoung Eun, An, Hongchan, Moon, Ju Won, Yeo, Hye Jin, Song, Youngsup, Chang, Sung Eun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458123/ https://www.ncbi.nlm.nih.gov/pubmed/36080217 http://dx.doi.org/10.3390/molecules27175449

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