Synthesis and Biological Evaluation of Cassane Diterpene (5α)-Vuacapane-8(14), 9(11)-Diene and of Some Related Compounds

A set of thirteen cassane-type diterpenes was synthesized and an expedient synthetic route was used to evaluate 14-desmethyl analogs of the most active tested cassane. The anti-inflammatory activities of these 13 compounds were evaluated on a lipopolysaccharide (LPS)-activated RAW 264.7 cell line by...

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Detalles Bibliográficos
Autores principales: Zentar, Houda, Jannus, Fatin, Medina-O’Donnell, Marta, Lupiáñez, José A., Justicia, José, Alvarez-Manzaneda, Ramón, Reyes-Zurita, Fernando J., Alvarez-Manzaneda, Enrique, Chahboun, Rachid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458217/
https://www.ncbi.nlm.nih.gov/pubmed/36080472
http://dx.doi.org/10.3390/molecules27175705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458217/
https://www.ncbi.nlm.nih.gov/pubmed/36080472
http://dx.doi.org/10.3390/molecules27175705

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