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Graft and Patient Outcomes of Kidney Transplant Tourism: A Single-Center Experience
Background The supply-demand mismatch between organ donor and patient waiting for transplant has led to the growth of transplant tourism. This type of transplant is considered unethical and illegal, as it is usually performed in poor environments and carries a higher risk of infectious, vascular, a...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458345/ https://www.ncbi.nlm.nih.gov/pubmed/36092382 http://dx.doi.org/10.1055/s-0042-1750715 |
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author | Altheaby, Abdulrahman Owaidah, Kenana Alotaibi, Aljowharah Salem, Rahaf Algain, Rihaf Alotaibi, Areij Alnasrullah, Ahmad Shaheen, Mohammed F. Tawhari, Mohammed Abdulgadir, Mohamad |
author_facet | Altheaby, Abdulrahman Owaidah, Kenana Alotaibi, Aljowharah Salem, Rahaf Algain, Rihaf Alotaibi, Areij Alnasrullah, Ahmad Shaheen, Mohammed F. Tawhari, Mohammed Abdulgadir, Mohamad |
author_sort | Altheaby, Abdulrahman |
collection | PubMed |
description | Background The supply-demand mismatch between organ donor and patient waiting for transplant has led to the growth of transplant tourism. This type of transplant is considered unethical and illegal, as it is usually performed in poor environments and carries a higher risk of infectious, vascular, and immunological complications. Methods In this single-centered retrospective cohort study, we compared patients who underwent transplant tourism to patients who were transplanted locally and followed up in our hospital from January 2015 to December 2018. Result A total of 254 local transplants and 60 patients from the transplant tourism group were included. Transplant tourism recipients were younger otherwise both groups were similar in gender, body mass index, diabetes, and hypertension. Recipients in the transplant tourism group had a significantly higher rate of delayed graft function (18.3% vs. 6.3%, p 0.005), acute rejection (40% vs. 7.9%, p < 0.001), and higher posttransplant infection in general. With more urological complications and higher graft failure at 3-years' follow-up (11.7% vs. 0.8%, p < 0.001). Conclusion Transplant tourism is associated with a higher risk of infection and poor graft outcomes. Extra efforts are required to cut down transplant tourism by educating patients about its clinical risk and ethical considerations. In addition, measures to increase the number of deceased donor pool to provide a better alternative options for patients are essential. |
format | Online Article Text |
id | pubmed-9458345 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-94583452022-09-09 Graft and Patient Outcomes of Kidney Transplant Tourism: A Single-Center Experience Altheaby, Abdulrahman Owaidah, Kenana Alotaibi, Aljowharah Salem, Rahaf Algain, Rihaf Alotaibi, Areij Alnasrullah, Ahmad Shaheen, Mohammed F. Tawhari, Mohammed Abdulgadir, Mohamad Avicenna J Med Background The supply-demand mismatch between organ donor and patient waiting for transplant has led to the growth of transplant tourism. This type of transplant is considered unethical and illegal, as it is usually performed in poor environments and carries a higher risk of infectious, vascular, and immunological complications. Methods In this single-centered retrospective cohort study, we compared patients who underwent transplant tourism to patients who were transplanted locally and followed up in our hospital from January 2015 to December 2018. Result A total of 254 local transplants and 60 patients from the transplant tourism group were included. Transplant tourism recipients were younger otherwise both groups were similar in gender, body mass index, diabetes, and hypertension. Recipients in the transplant tourism group had a significantly higher rate of delayed graft function (18.3% vs. 6.3%, p 0.005), acute rejection (40% vs. 7.9%, p < 0.001), and higher posttransplant infection in general. With more urological complications and higher graft failure at 3-years' follow-up (11.7% vs. 0.8%, p < 0.001). Conclusion Transplant tourism is associated with a higher risk of infection and poor graft outcomes. Extra efforts are required to cut down transplant tourism by educating patients about its clinical risk and ethical considerations. In addition, measures to increase the number of deceased donor pool to provide a better alternative options for patients are essential. Thieme Medical and Scientific Publishers Pvt. Ltd. 2022-08-16 /pmc/articles/PMC9458345/ /pubmed/36092382 http://dx.doi.org/10.1055/s-0042-1750715 Text en Avicenna Journal of Medicine. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited. |
spellingShingle | Altheaby, Abdulrahman Owaidah, Kenana Alotaibi, Aljowharah Salem, Rahaf Algain, Rihaf Alotaibi, Areij Alnasrullah, Ahmad Shaheen, Mohammed F. Tawhari, Mohammed Abdulgadir, Mohamad Graft and Patient Outcomes of Kidney Transplant Tourism: A Single-Center Experience |
title | Graft and Patient Outcomes of Kidney Transplant Tourism: A Single-Center Experience |
title_full | Graft and Patient Outcomes of Kidney Transplant Tourism: A Single-Center Experience |
title_fullStr | Graft and Patient Outcomes of Kidney Transplant Tourism: A Single-Center Experience |
title_full_unstemmed | Graft and Patient Outcomes of Kidney Transplant Tourism: A Single-Center Experience |
title_short | Graft and Patient Outcomes of Kidney Transplant Tourism: A Single-Center Experience |
title_sort | graft and patient outcomes of kidney transplant tourism: a single-center experience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458345/ https://www.ncbi.nlm.nih.gov/pubmed/36092382 http://dx.doi.org/10.1055/s-0042-1750715 |
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