Chemoenzymatic labeling of DNA methylation patterns for single-molecule epigenetic mapping

DNA methylation, specifically, methylation of cytosine (C) nucleotides at the 5-carbon position (5-mC), is the most studied and significant epigenetic modification. Here we developed a chemoenzymatic procedure to fluorescently label non-methylated cytosines in CpG context, allowing epigenetic profil...

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Detalles Bibliográficos
Autores principales: Gabrieli, Tslil, Michaeli, Yael, Avraham, Sigal, Torchinsky, Dmitry, Margalit, Sapir, Schütz, Leonie, Juhasz, Matyas, Coruh, Ceyda, Arbib, Nissim, Zhou, Zhaohui Sunny, Law, Julie A, Weinhold, Elmar, Ebenstein, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458417/
https://www.ncbi.nlm.nih.gov/pubmed/35657088
http://dx.doi.org/10.1093/nar/gkac460

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