Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNA(Asn), tRNA(Gln), tRNA(Glu) and tRNA(Pro)

Pseudouridine (Ψ) at position 55 in tRNAs plays an important role in their structure and function. This modification is catalyzed by TruB/Pus4/Cbf5 family of pseudouridine synthases in bacteria and yeast. However, the mechanism of TRUB family underlying the formation of Ψ55 in the mammalian tRNAs is...

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Detalles Bibliográficos
Autores principales: Jia, Zidong, Meng, Feilong, Chen, Hui, Zhu, Gao, Li, Xincheng, He, Yunfan, Zhang, Liyao, He, Xiao, Zhan, Huisen, Chen, Mengquan, Ji, Yanchun, Wang, Meng, Guan, Min-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458420/
https://www.ncbi.nlm.nih.gov/pubmed/36018806
http://dx.doi.org/10.1093/nar/gkac698

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