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The toxin–antitoxin RNA guards of CRISPR-Cas evolved high specificity through repeat degeneration

Recent discovery of ectopic repeats (outside CRISPR arrays) provided unprecedented insights into the nondefense roles of CRISPR-Cas. A striking example is the addiction module CreTA (CRISPR-regulated toxin–antitoxins), where one or two (in most cases) ectopic repeats produce CRISPR-resembling antito...

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Detalles Bibliográficos
Autores principales:	Cheng, Feiyue, Wu, Aici, Liu, Chao, Cao, Xifeng, Wang, Rui, Shu, Xian, Wang, Lingyun, Zhang, Yihan, Xiang, Hua, Li, Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458426/ https://www.ncbi.nlm.nih.gov/pubmed/36018812 http://dx.doi.org/10.1093/nar/gkac712

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