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Iso-FRET: an isothermal competition assay to analyze quadruplex formation in vitro
Algorithms have been widely used to predict G-quadruplexes (G4s)-prone sequences. However, an experimental validation of these predictions is generally required. We previously reported a high-throughput technique to evidence G4 formation in vitro called FRET-MC. This method, while convenient and rep...
Autores principales: | Luo, Yu, Verga, Daniela, Mergny, Jean-Louis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458428/ https://www.ncbi.nlm.nih.gov/pubmed/35670668 http://dx.doi.org/10.1093/nar/gkac465 |
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