Topoisomerase IIA in adult NSCs regulates SVZ neurogenesis by transcriptional activation of Usp37

Topoisomerase IIA (TOP2a) has traditionally been known as an important nuclear enzyme that resolves entanglements and relieves torsional stress of DNA double strands. However, its function in genomic transcriptional regulation remains largely unknown, especially during adult neurogenesis. Here, we s...

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Detalles Bibliográficos
Autores principales: Qin, Shangyao, Yuan, Yimin, Huang, Xiao, Tan, Zijian, Hu, Xin, Liu, Hong, Pu, Yingyan, Ding, Yu-qiang, Su, Zhida, He, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458435/
https://www.ncbi.nlm.nih.gov/pubmed/36029179
http://dx.doi.org/10.1093/nar/gkac731

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