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Stochastically multimerized ParB orchestrates DNA assembly as unveiled by single-molecule analysis

The tripartite ParABS system mediates chromosome segregation in a wide range of bacteria. Dimeric ParB was proposed to nucleate on parS sites and spread to neighboring DNA. However, how properly distributed ParB dimers further compact chromosomal DNA into a higher-order nucleoprotein complex for par...

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Detalles Bibliográficos
Autores principales: Guo, Lijuan, Zhao, Yilin, Zhang, Qian, Feng, Ying, Bi, Lulu, Zhang, Xia, Wang, Teng, Liu, Cong, Ma, Hanhui, Sun, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458438/
https://www.ncbi.nlm.nih.gov/pubmed/35904809
http://dx.doi.org/10.1093/nar/gkac651