What is a supercoiling-sensitive gene? Insights from topoisomerase I inhibition in the Gram-negative bacterium Dickeya dadantii

DNA supercoiling is an essential mechanism of bacterial chromosome compaction, whose level is mainly regulated by topoisomerase I and DNA gyrase. Inhibiting either of these enzymes with antibiotics leads to global supercoiling modifications and subsequent changes in global gene expression. In previo...

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Detalles Bibliográficos
Autores principales: Pineau, Maïwenn, Martis B., Shiny, Forquet, Raphaël, Baude, Jessica, Villard, Camille, Grand, Lucie, Popowycz, Florence, Soulère, Laurent, Hommais, Florence, Nasser, William, Reverchon, Sylvie, Meyer, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458453/
https://www.ncbi.nlm.nih.gov/pubmed/35950487
http://dx.doi.org/10.1093/nar/gkac679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458453/
https://www.ncbi.nlm.nih.gov/pubmed/35950487
http://dx.doi.org/10.1093/nar/gkac679

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