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The cytoprotective sequestration activity of small heat shock proteins is evolutionarily conserved

The chaperone-mediated sequestration of misfolded proteins into inclusions is a pivotal cellular strategy to maintain proteostasis in Saccharomyces cerevisiae, executed by small heat shock proteins (sHsps) Hsp42 and Btn2. Direct homologs of Hsp42 and Btn2 are absent in other organisms, questioning w...

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Detalles Bibliográficos
Autores principales:	Shrivastava, Aseem, Sandhof, Carl Alexander, Reinle, Kevin, Jawed, Areeb, Ruger-Herreros, Carmen, Schwarz, Dominic, Creamer, Declan, Nussbaum-Krammer, Carmen, Mogk, Axel, Bukau, Bernd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458469/ https://www.ncbi.nlm.nih.gov/pubmed/36069810 http://dx.doi.org/10.1083/jcb.202202149

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