Piezo1 regulates cholesterol biosynthesis to influence neural stem cell fate during brain development

Mechanical forces and tissue mechanics influence the morphology of the developing brain, but the underlying molecular mechanisms have been elusive. Here, we examine the role of mechanotransduction in brain development by focusing on Piezo1, a mechanically activated ion channel. We find that Piezo1 d...

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Detalles Bibliográficos
Autores principales: Nourse, Jamison L., Leung, Vivian M., Abuwarda, Hamid, Evans, Elizabeth L., Izquierdo-Ortiz, Esmeralda, Ly, Alan T., Truong, Nguyen, Smith, Samantha, Bhavsar, Harsh, Bertaccini, Gabriella, Monuki, Edwin S., Panicker, Mitradas M., Pathak, Medha M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458470/
https://www.ncbi.nlm.nih.gov/pubmed/36069933
http://dx.doi.org/10.1085/jgp.202213084

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