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Regulation associated modules reflect 3D genome modularity associated with chromatin activity

The 3D genome has been shown to be organized into modules including topologically associating domains (TADs) and compartments that are primarily defined by spatial contacts from Hi-C. There exists a gap to investigate whether and how the spatial modularity of the chromatin is related to the function...

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Detalles Bibliográficos
Autores principales: Zheng, Lina, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458634/
https://www.ncbi.nlm.nih.gov/pubmed/36075900
http://dx.doi.org/10.1038/s41467-022-32911-y