Paternal low protein diet perturbs inter-generational metabolic homeostasis in a tissue-specific manner in mice

The underlying mechanisms driving paternally-programmed metabolic disease in offspring remain poorly defined. We fed male C57BL/6 mice either a control normal protein diet (NPD; 18% protein) or an isocaloric low protein diet (LPD; 9% protein) for a minimum of 8 weeks. Using artificial insemination,...

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Detalles Bibliográficos
Autores principales: Morgan, Hannah L., Furse, Samuel, Dias, Irundika H. K., Shabir, Kiran, Castellanos, Marcos, Khan, Iqbal, May, Sean T., Holmes, Nadine, Carlile, Matthew, Sang, Fei, Wright, Victoria, Koulman, Albert, Watkins, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458637/
https://www.ncbi.nlm.nih.gov/pubmed/36075960
http://dx.doi.org/10.1038/s42003-022-03914-8

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