Single nucleus transcriptomic analysis of rat nucleus accumbens reveals cell type-specific patterns of gene expression associated with volitional morphine intake

Opioid exposure is known to cause transcriptomic changes in the nucleus accumbens (NAc). However, no studies to date have investigated cell type-specific transcriptomic changes associated with volitional opioid taking. Here, we use single nucleus RNA sequencing (snRNAseq) to comprehensively characte...

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Detalles Bibliográficos
Autores principales: Reiner, Benjamin C., Zhang, Yafang, Stein, Lauren M., Perea, Emilie Dávila, Arauco-Shapiro, Gabriella, Ben Nathan, Jennifer, Ragnini, Kael, Hayes, Matthew R., Ferraro, Thomas N., Berrettini, Wade H., Schmidt, Heath D., Crist, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458645/
https://www.ncbi.nlm.nih.gov/pubmed/36075888
http://dx.doi.org/10.1038/s41398-022-02135-1

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