Early impairment of cortical circuit plasticity and connectivity in the 5XFAD Alzheimer’s disease mouse model

Genetic risk factors for neurodegenerative disorders, such as Alzheimer’s disease (AD), are expressed throughout the life span. How these risk factors affect early brain development and function remain largely unclear. Analysis of animal models with high constructive validity for AD, such as the 5xF...

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Detalles Bibliográficos
Autores principales: Chen, Chang, Ma, Xiaokuang, Wei, Jing, Shakir, Neha, Zhang, Jessica K., Zhang, Le, Nehme, Antoine, Cui, Yuehua, Ferguson, Deveroux, Bai, Feng, Qiu, Shenfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458752/
https://www.ncbi.nlm.nih.gov/pubmed/36075886
http://dx.doi.org/10.1038/s41398-022-02132-4

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