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Model-informed experimental design recommendations for distinguishing intrinsic and acquired targeted therapeutic resistance in head and neck cancer

The promise of precision medicine has been limited by the pervasive resistance to many targeted therapies for cancer. Inferring the timing (i.e., pre-existing or acquired) and mechanism (i.e., drug-induced) of such resistance is crucial for designing effective new therapeutics. This paper studies ce...

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Detalles Bibliográficos
Autores principales:	Cárdenas, Santiago D., Reznik, Constance J., Ranaweera, Ruchira, Song, Feifei, Chung, Christine H., Fertig, Elana J., Gevertz, Jana L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458753/ https://www.ncbi.nlm.nih.gov/pubmed/36075912 http://dx.doi.org/10.1038/s41540-022-00244-7

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