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Current intraoperative storage and handling practices of autologous bypass conduit: A survey of the royal australasian college of surgeons

During bypass surgery for peripheral arterial occlusive disease and ischaemic heart disease, autologous graft conduit including great saphenous veins and radial arteries are frequently stored in solution. Endothelial damage adversely affects the performance and patency of autologous bypass grafts, a...

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Autores principales: Haymet, AB, Pinto, N, Peden, S, Cohen, T, Vallely, MP, McGiffin, D, Naidoo, R, Jenkins, J, Suen, JY, Fraser, JF
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458927/
https://www.ncbi.nlm.nih.gov/pubmed/36090334
http://dx.doi.org/10.3389/fsurg.2022.956177
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author Haymet, AB
Pinto, N
Peden, S
Cohen, T
Vallely, MP
McGiffin, D
Naidoo, R
Jenkins, J
Suen, JY
Fraser, JF
author_facet Haymet, AB
Pinto, N
Peden, S
Cohen, T
Vallely, MP
McGiffin, D
Naidoo, R
Jenkins, J
Suen, JY
Fraser, JF
author_sort Haymet, AB
collection PubMed
description During bypass surgery for peripheral arterial occlusive disease and ischaemic heart disease, autologous graft conduit including great saphenous veins and radial arteries are frequently stored in solution. Endothelial damage adversely affects the performance and patency of autologous bypass grafts, and intraoperative graft storage solutions have been shown to influence this process. The distribution of storage solutions currently used amongst Cardiothoracic and Vascular Surgeons from Australia and New Zealand is not well defined in the literature. The aim of this study was to determine current practices regarding autologous graft storage and handling amongst this cohort of surgeons, and discuss their potential relevance in the context of early graft failure. From this survey, the most frequently used storage solutions were heparinized saline for great saphenous veins, and pH-buffered solutions for radial arteries. Duration of storage was 30–45 min for almost half of respondents, although responses to this question were limited. Further research is required to investigate whether ischaemic endothelial injury generates a prothrombotic state, whether different storage media can alter this state, and whether this is directly associated with clinical outcomes of interest such as early graft failure.
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spelling pubmed-94589272022-09-10 Current intraoperative storage and handling practices of autologous bypass conduit: A survey of the royal australasian college of surgeons Haymet, AB Pinto, N Peden, S Cohen, T Vallely, MP McGiffin, D Naidoo, R Jenkins, J Suen, JY Fraser, JF Front Surg Surgery During bypass surgery for peripheral arterial occlusive disease and ischaemic heart disease, autologous graft conduit including great saphenous veins and radial arteries are frequently stored in solution. Endothelial damage adversely affects the performance and patency of autologous bypass grafts, and intraoperative graft storage solutions have been shown to influence this process. The distribution of storage solutions currently used amongst Cardiothoracic and Vascular Surgeons from Australia and New Zealand is not well defined in the literature. The aim of this study was to determine current practices regarding autologous graft storage and handling amongst this cohort of surgeons, and discuss their potential relevance in the context of early graft failure. From this survey, the most frequently used storage solutions were heparinized saline for great saphenous veins, and pH-buffered solutions for radial arteries. Duration of storage was 30–45 min for almost half of respondents, although responses to this question were limited. Further research is required to investigate whether ischaemic endothelial injury generates a prothrombotic state, whether different storage media can alter this state, and whether this is directly associated with clinical outcomes of interest such as early graft failure. Frontiers Media S.A. 2022-08-26 /pmc/articles/PMC9458927/ /pubmed/36090334 http://dx.doi.org/10.3389/fsurg.2022.956177 Text en © 2022 Haymet, Pinto, Peden, Cohen, Vallely, McGiffin, Naidoo, Jenkins, Suen and Fraser. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Haymet, AB
Pinto, N
Peden, S
Cohen, T
Vallely, MP
McGiffin, D
Naidoo, R
Jenkins, J
Suen, JY
Fraser, JF
Current intraoperative storage and handling practices of autologous bypass conduit: A survey of the royal australasian college of surgeons
title Current intraoperative storage and handling practices of autologous bypass conduit: A survey of the royal australasian college of surgeons
title_full Current intraoperative storage and handling practices of autologous bypass conduit: A survey of the royal australasian college of surgeons
title_fullStr Current intraoperative storage and handling practices of autologous bypass conduit: A survey of the royal australasian college of surgeons
title_full_unstemmed Current intraoperative storage and handling practices of autologous bypass conduit: A survey of the royal australasian college of surgeons
title_short Current intraoperative storage and handling practices of autologous bypass conduit: A survey of the royal australasian college of surgeons
title_sort current intraoperative storage and handling practices of autologous bypass conduit: a survey of the royal australasian college of surgeons
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458927/
https://www.ncbi.nlm.nih.gov/pubmed/36090334
http://dx.doi.org/10.3389/fsurg.2022.956177
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