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Design, synthesis and biological evaluation of novel biphenylsulfonamide derivatives as selective AT(2) receptor antagonists

A novel series of benzenesulfonamide derivatives that selectively act on the AT(2) receptor have been designed and synthesized. The binding affinity and functional activity were evaluated by radio-ligand binding analysis and cell neurite outgrowth assay, respectively. The compounds 8d, 8h, 8i, 8j, 8...

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Detalles Bibliográficos
Autores principales:	Wang, Danhui, Zhao, Wenjie, Zhang, Zuzhi, Zhang, Yanchun, Li, Jiaming, Huang, Weijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9458978/ https://www.ncbi.nlm.nih.gov/pubmed/36092654 http://dx.doi.org/10.3389/fchem.2022.984717

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