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A possible mechanism to the antidepressant-like effects of 20 (S)-protopanaxadiol based on its target protein 14-3-3 ζ

BACKGROUND: Ginsenosides and their metabolites have antidepressant-like effects, but the underlying mechanisms remain unclear. We previously identified 14-3-3 ζ as one of the target proteins of 20 (S)-protopanaxadiol (PPD), a fully deglycosylated ginsenoside metabolite. METHODS: Corticosterone (CORT...

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Detalles Bibliográficos
Autores principales:	Chen, Lin, Li, Ruimei, Chen, Feiyan, Zhang, Hantao, Zhu, Zhu, Xu, Shuyi, Cheng, Yao, Zhao, Yunan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459030/ https://www.ncbi.nlm.nih.gov/pubmed/36090685 http://dx.doi.org/10.1016/j.jgr.2021.12.004

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