Cargando…

Crosstalk between acetylation and the tyrosination/detyrosination cycle of α-tubulin in Alzheimer’s disease

Microtubules (MTs) support a variety of neuronal functions, such as maintenance of cell structure, transport, and synaptic plasticity. Neuronal MTs are highly heterogeneous due to several tubulin isotypes and the presence of multiple post-translational modifications, such as detyrosination and acety...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martínez-Hernández, José, Parato, Julie, Sharma, Aditi, Soleilhac, Jean-Marc, Qu, Xiaoyi, Tein, Ellen, Sproul, Andrew, Andrieux, Annie, Goldberg, Yves, Moutin, Marie-Jo, Bartolini, Francesca, Peris, Leticia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459041/ https://www.ncbi.nlm.nih.gov/pubmed/36092705 http://dx.doi.org/10.3389/fcell.2022.926914

Ejemplares similares

Tubulin tyrosination regulates synaptic function and is disrupted in Alzheimer’s disease
por: Peris, Leticia, et al.
Publicado: (2022)

Cap-Gly Proteins at Microtubule Plus Ends: Is EB1 Detyrosination Involved?
por: Bosson, Anouk, et al.
Publicado: (2012)

Tubulin post‐translational modifications control neuronal development and functions
por: Moutin, Marie‐Jo, et al.
Publicado: (2020)

Ultrastructural colocalization of tyrosinated and detyrosinated alpha- tubulin in interphase and mitotic cells
Publicado: (1986)

Posttranslational modifications of alpha-tubulin: acetylated and detyrosinated forms in axons of rat cerebellum
Publicado: (1987)

Assembly and turnover of detyrosinated tubulin in vivo
Publicado: (1987)

Structural basis of tubulin detyrosination by vasohibins
por: Li, Faxiang, et al.
Publicado: (2019)

Enhanced stability of microtubules enriched in detyrosinated tubulin is not a direct function of detyrosination level
Publicado: (1988)

Posttranslational modifications of alpha tubulin: detyrosination and acetylation differentiate populations of interphase microtubules in cultured cells
Publicado: (1988)

Hydrogen Peroxide Induces α-Tubulin Detyrosination and Acetylation and Impacts Breast Cancer Metastatic Phenotypes
por: Stemberger, Megan B., et al.
Publicado: (2023)

Detyrosinated microtubule arrays drive myofibrillar malformations in mdx muscle fibers
por: Harriot, Anicca D., et al.
Publicado: (2023)

Motor-dependent microtubule disassembly driven by tubulin tyrosination
por: Peris, Leticia, et al.
Publicado: (2009)

The posttranslational modification of tubulin undergoes a switch from detyrosination to acetylation as epithelial cells become polarized
por: Quinones, Geraldine B., et al.
Publicado: (2011)

Tubulin detyrosination promotes human trophoblast syncytium formation
por: Wang, Rui, et al.
Publicado: (2019)

Structural insights into tubulin detyrosination by vasohibins-SVBP complex
por: Liu, Xi, et al.
Publicado: (2019)

Structural basis of tubulin detyrosination by VASH2/SVBP heterodimer
por: Zhou, Chen, et al.
Publicado: (2019)

Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy
por: Schuldt, Maike, et al.
Publicado: (2021)

VASH1–SVBP and VASH2–SVBP generate different detyrosination profiles on microtubules
por: Ramirez-Rios, Sacnicte, et al.
Publicado: (2022)

Spatial and temporal colocalization of the Golgi apparatus and microtubules rich in detyrosinated tubulin
Publicado: (1990)

Postpolymerization detyrosination of alpha-tubulin: a mechanism for subcellular differentiation of microtubules
Publicado: (1987)

Desmin intermediate filaments and tubulin detyrosination stabilize growing microtubules in the cardiomyocyte
por: Salomon, Alexander K., et al.
Publicado: (2022)

α-Tubulin detyrosination links the suppression of MCAK activity with taxol cytotoxicity
por: Lopes, Danilo, et al.
Publicado: (2022)

Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation
por: Eira, Jessica, et al.
Publicado: (2021)

Suppression of tubulin detyrosination by parthenolide recruits the plant-specific kinesin KCH to cortical microtubules
por: Schneider, Natalie, et al.
Publicado: (2015)

α-Tubulin detyrosination impairs mitotic error correction by suppressing MCAK centromeric activity
por: Ferreira, Luísa T., et al.
Publicado: (2020)

Evidence for new C-terminally truncated variants of α- and β-tubulins
por: Aillaud, Chrystelle, et al.
Publicado: (2016)

Tubulin Tyrosination Is Required for the Proper Organization and Pathfinding of the Growth Cone
por: Marcos, Séverine, et al.
Publicado: (2009)

Evaluation of α-tubulin, detyrosinated α-tubulin, and vimentin in CTCs: identification of the interaction between CTCs and blood cells through cytoskeletal elements
por: Kallergi, G., et al.
Publicado: (2018)

Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends
por: Peris, Leticia, et al.
Publicado: (2006)

Mathematical modeling of the microtubule detyrosination/tyrosination cycle for cell-based drug screening design
por: Grignard, Jeremy, et al.
Publicado: (2022)

Structural basis of tubulin tyrosination by tubulin tyrosine ligase
por: Prota, Andrea E., et al.
Publicado: (2013)

Loss of Deacetylation Enzymes Hdac6 and Sirt2 Promotes Acetylation of Cytoplasmic Tubulin, but Suppresses Axonemal Acetylation in Zebrafish Cilia
por: Łysyganicz, Paweł K., et al.
Publicado: (2021)

Pseudophosphatase MK-STYX Alters Histone Deacetylase 6 Cytoplasmic Localization, Decreases Its Phosphorylation, and Increases Detyrosination of Tubulin
por: Cao, Yuming, et al.
Publicado: (2019)

RBM14 Modulates Tubulin Acetylation and Regulates Spindle Morphology During Meiotic Maturation in Mouse Oocytes
por: Qin, Hao, et al.
Publicado: (2021)

INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cells
por: Andrés-Delgado, Laura, et al.
Publicado: (2012)

Parthenolide and costunolide reduce microtentacles and tumor cell attachment by selectively targeting detyrosinated tubulin independent from NF-κB inhibition
por: Whipple, Rebecca A, et al.
Publicado: (2013)

Quantitative Profiling of Lysine Acetylation Reveals Dynamic Crosstalk between Receptor Tyrosine Kinases and Lysine Acetylation
por: Bryson, Bryan D., et al.
Publicado: (2015)

Effects of tubulin acetylation and tubulin acetyltransferase binding on microtubule structure
por: Howes, Stuart C., et al.
Publicado: (2014)

Characterization of the tubulin-tyrosine ligase
Publicado: (1993)

RASSF1A Regulates Spindle Organization by Modulating Tubulin Acetylation via SIRT2 and HDAC6 in Mouse Oocytes
por: Jeon, Hyuk-Joon, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ulmivj4u8oh7f9h8f37cup78vi