Amphotericin B release rate is the link between drug status in the liposomal bilayer and toxicity

Amphotericin B (AmB) is an amphiphilic drug commonly formulated in liposomes and administered intravenously to treat systemic fungal infections. Recent studies on the liposomal drug product have shed light on the AmB aggregation status in the bilayer, which heat treatment (curing) modifies. Although...

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Detalles Bibliográficos
Autores principales: Svirkin, Yuri, Lee, Jaeweon, Marx, Richard, Yoon, Seongkyu, Landrau, Nelson, Kaisar, Md Abul, Qin, Bin, Park, Jin H., Alam, Khondoker, Kozak, Darby, Wang, Yan, Xu, Xiaoming, Zheng, Jiwen, Rivnay, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2022
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9459057/
https://www.ncbi.nlm.nih.gov/pubmed/36105314
http://dx.doi.org/10.1016/j.ajps.2022.04.007

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